Molecular structure of rac Demethyl Citalopram-d3 Hydrochloride, CAS Number: 1189650-18-7
rac Demethyl Citalopram-d3 Hydrochloride (CAS 1189650-18-7)
Alternate Names:
1-(4-Fluoro-phenyl)-1-[3-(methyl-d3)amino-propyl]-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrochloride; 1-[3-(Methylamino-d3)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
Application:
rac Demethyl Citalopram-d3 Hydrochloride is a deuterium-labeled analog of Citalopram
CAS Number:
1189650-18-7
Molecular Weight:
349.84
Molecular Formula:
C19H16D3FN2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
rac Demethyl Citalopram-d3 Hydrochloride is a deuterium-labeled derivative of Citalopram (sc-201123). Citalopram is a selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavor.
rac Demethyl Citalopram-d3 Hydrochloride (CAS 1189650-18-7) References
- Plasma membrane monoamine transporters: structure, regulation and function. | Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
- The effect of citalopram on gene expression profile of Alzheimer lymphocytes. | Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
- Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study. | Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
- Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms. | Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
rac Demethyl Citalopram-d3 Hydrochloride, 1 mg | sc-219820 | 1 mg | $406.00 | |||
rac Demethyl Citalopram-d3 Hydrochloride, 10 mg | sc-219820A | 10 mg | $2913.00 |