3-hydroxy-2-methylpropanoic acid (CAS 2068-83-9)
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3-Hydroxyisobutyric acid is a compound that functions as an intermediate in the valine catabolic pathway. It is involved in the breakdown of valine, an amino acid, and is produced as a byproduct of this process. 3-Hydroxyisobutyric acid acts as a substrate for the enzyme 3-hydroxyisobutyrate dehydrogenase, which catalyzes the conversion of 3-Hydroxyisobutyric acid to methylmalonic semialdehyde. This enzymatic reaction is a key step in the valine catabolic pathway, contributing to the metabolism of valine within the cell. By participating in this metabolic pathway, 3-Hydroxyisobutyric acid plays a specific role in the cellular utilization of valine and contributes to the regulation of amino acid metabolism. Its mechanism of action involves its enzymatic conversion by 3-hydroxyisobutyrate dehydrogenase, which is for the proper functioning of the valine catabolic pathway.
3-hydroxy-2-methylpropanoic acid (CAS 2068-83-9) References
- Branched-chain amino acid enriched supplements as therapy for liver disease. | Charlton, M. 2006. J Nutr. 136: 295S-8S. PMID: 16365102
- The anaplerotic flux and ammonia detoxification in hepatic encephalopathy. | Zwingmann, C. 2007. Metab Brain Dis. 22: 235-49. PMID: 17823857
- ATPase-associated antigen (M2): marker antigen for serological diagnosis of primary biliary cirrhosis. | Berg, PA., et al. 1982. Lancet. 2: 1423-6. PMID: 6184586
- Generation of ketone bodies from leucine by cultured astroglial cells. | Bixel, MG. and Hamprecht, B. 1995. J Neurochem. 65: 2450-61. PMID: 7595539
- Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons. | Bröer, S., et al. 1997. J Biol Chem. 272: 30096-102. PMID: 9374487
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-hydroxy-2-methylpropanoic acid, 1 mg | sc-212704 | 1 mg | $286.00 | |||
3-hydroxy-2-methylpropanoic acid, 10 mg | sc-212704A | 10 mg | $612.00 |