Date published: 2025-12-14

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Rabeprazole Sulfone (CAS 117976-47-3)

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Application:
Rabeprazole Sulfone is a metabolite of Rabeprazole
CAS Number:
117976-47-3
Molecular Weight:
375.44
Molecular Formula:
C18H21N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A metabolite of Rabeprazole.


Rabeprazole Sulfone (CAS 117976-47-3) References

  1. Different contribution of CYP2C19 in the in vitro metabolism of three proton pump inhibitors.  |  Kita, T., et al. 2003. Biol Pharm Bull. 26: 386-90. PMID: 12612455
  2. Stereoselective metabolism of rabeprazole-thioether to rabeprazole by human liver microsomes.  |  Miura, M., et al. 2006. Eur J Clin Pharmacol. 62: 113-7. PMID: 16389533
  3. Enantioselective disposition of lansoprazole and rabeprazole in human plasma.  |  Miura, M. 2006. Yakugaku Zasshi. 126: 395-402. PMID: 16755125
  4. Effects of clarithromycin and verapamil on rabeprazole pharmacokinetics between CYP2C19 genotypes.  |  Shimizu, M., et al. 2006. Eur J Clin Pharmacol. 62: 597-603. PMID: 16783561
  5. Development and Validation of a UPLC Method by the QbD-Approach for the Estimation of Rabeprazole and Levosulpiride from Capsules.  |  Thummala, VR., et al. 2014. Sci Pharm. 82: 307-26. PMID: 24959404
  6. Application of a liquid chromatographic/tandem mass spectrometric method to a urinary excretion study of rabeprazole and two of its metabolites in healthy human urine.  |  Lu, C., et al. 2015. J Chromatogr B Analyt Technol Biomed Life Sci. 988: 75-80. PMID: 25755073
  7. Stereoselective and nonstereoselective pharmacokinetics of rabeprazole - an overview.  |  Dash, RP., et al. 2018. Xenobiotica. 48: 422-432. PMID: 28294690
  8. Synthesis of metabolites and related substances of rabeprazole, an anti-ulcerative drug  |  Reddy, G. M., Mukkanti, K., Bhaskar, B. V., & Reddy, P. P. 2008. Synthetic Communications. 39(2): 278-290.
  9. Simultaneous determination of rabeprazole enantiomers and their four metabolites after intravenous administration in beagle dogs by a stereoselective HPLC-MS/MS method and its application in pharmacokinetic studies  |  Cao, N., Liu, L., Hao, Y. B., Sun, L. L., Zou, Q. G., Ma, X. L., & **ong, K. H. 2016. Analytical methods. 8(6): 1405-1414.
  10. An application of continuous flow microreactor in the synthesis and extraction of rabeprazole  |  Duan, Z., Wang, Y., Zhang, L., Cao, X., Fu, L., Li, Z., & Zhang, J. 2021. International Journal of Chemical Reactor Engineering. 19(3): 287-294.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rabeprazole Sulfone, 5 mg

sc-208256
5 mg
$330.00