Date published: 2025-12-18

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Rabeprazole Sulfide (CAS 117977-21-6)

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Application:
Rabeprazole Sulfide is a metabolite of Rabeprazole
CAS Number:
117977-21-6
Molecular Weight:
343.44
Molecular Formula:
C18H21N3O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Rabeprazole Sulfide is a metabolite of Rabeprazole.


Rabeprazole Sulfide (CAS 117977-21-6) References

  1. Stereoselective metabolism of rabeprazole-thioether to rabeprazole by human liver microsomes.  |  Miura, M., et al. 2006. Eur J Clin Pharmacol. 62: 113-7. PMID: 16389533
  2. Empirical regioselectivity models for human cytochromes P450 3A4, 2D6, and 2C9.  |  Sheridan, RP., et al. 2007. J Med Chem. 50: 3173-84. PMID: 17579382
  3. Stereoselective disposition of proton pump inhibitors.  |  Andersson, T. and Weidolf, L. 2008. Clin Drug Investig. 28: 263-79. PMID: 18407713
  4. In vitro metabolic stability of moisture-sensitive rabeprazole in human liver microsomes and its modulation by pharmaceutical excipients.  |  Ren, S., et al. 2008. Arch Pharm Res. 31: 406-13. PMID: 18409057
  5. Antiinfectives targeting enzymes and the proton motive force.  |  Feng, X., et al. 2015. Proc Natl Acad Sci U S A. 112: E7073-82. PMID: 26644565
  6. Effect of CYP2C19 Gene Polymorphisms on Proton Pump Inhibitor, Amoxicillin, and Levofloxacin Triple Therapy for Eradication of Helicobacter Pylori.  |  Lin, YA., et al. 2017. Med Sci Monit. 23: 2701-2707. PMID: 28577017
  7. Interconnection of sulfides and sulfoxides in medicinal chemistry.  |  Surur, AS., et al. 2019. Arch Pharm (Weinheim). 352: e1800248. PMID: 30521146
  8. Pharmacokinetic evaluation of differential drug release formulations of rabeprazole in dogs.  |  Patel, H., et al. 2019. Drug Dev Ind Pharm. 45: 1459-1467. PMID: 31216902
  9. DNA unchained: two assays to discover and study inhibitors of the DNA clustering function of barrier-to-autointegration factor.  |  Burger, M., et al. 2020. Sci Rep. 10: 12301. PMID: 32704141
  10. Production of an O-desmethylated product, a major human metabolite, of rabeprazole sulfide by bacterial P450 enzymes.  |  Cao, NT., et al. 2023. Enzyme Microb Technol. 171: 110328. PMID: 37751627
  11. Inhibiting effects of rabeprazole sulfide on the corrosion of mild steel in acidic chloride solution  |  Pavithra, M. K., Venkatesha, T. V., & Punith Kumar, M. K. 2013. International Journal of Electrochemistry. 2013(1): 714372.
  12. An application of continuous flow microreactor in the synthesis and extraction of rabeprazole  |  Duan, Z., Wang, Y., Zhang, L., Cao, X., Fu, L., Li, Z., & Zhang, J. 2021. International Journal of Chemical Reactor Engineering. 19(3): 287-294.
  13. An O-Demethylation Metabolite of Rabeprazole Sulfide by Cunninghamella Blakesleeana 3.970 Biotransformation  |  Song, M., Zhu, H., Wang, J., Xu, W., & Xu, W. 2022. Catalysts. 13(1): 15.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rabeprazole Sulfide, 5 mg

sc-219766
5 mg
$290.00