Rab 3B Antibody (48-K2) is a mouse monoclonal IgG2a antibody that detects Rab 3B protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 3B antibody (48-K2) is available as a non-conjugated format. Rab 3B plays a crucial role in regulating vesicle trafficking, particularly in neurotransmitter and hormone transport, which is essential for proper cellular communication and function. Located primarily in the cytoplasm and associated with secretory vesicles, Rab 3B is involved in docking and fusion of vesicles with target membranes, facilitating content release into extracellular space. This process is vital for neurotransmission and hormone secretion, highlighting Rab 3B′s importance in maintaining physiological homeostasis. Rab 3B belongs to the Ras-related superfamily of guanine nucleotide-binding proteins, exhibiting significant homology with Ras p21, and functions with various interacting proteins that assist in vesicle transport. With at least eight members identified in the Rab family, each protein localizes to specific stages of membrane transport pathways, underscoring the complexity and specificity of intracellular trafficking mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 3B Antibody (48-K2) | sc-81911 | 100 µg/ml | $333.00 |