Date published: 2025-10-19

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Rab 36 Antibody (379.2): sc-81916

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Datasheets
  • Rab 36 Antibody (379.2) is a mouse monoclonal IgG2a κ Rab 36 antibody provided at 50 µg/0.5 ml
  • raised against recombinant Rab 36 of human origin
  • recommended for detection of Rab 36 of human origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rab 36 Antibody (379.2). This work is in progress.

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    Rab 36 Antibody (379.2) is a mouse monoclonal IgG2a kappa light chain antibody that detects Rab 36 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 36 antibody (379.2) is available as a non-conjugated format. Rab 36 is a member of the Ras-related superfamily of guanine nucleotide-binding proteins, which includes various subfamilies such as R-Ras, Rap, Ral/Rec, and Rho/Rab. Rab 36 plays a crucial role in transporting newly synthesized proteins from the endoplasmic reticulum to the Golgi complex and secretory vesicles, a process essential for maintaining cellular function and homeostasis. Proper functioning of Rab proteins is vital for both endocytosis and biosynthetic protein transport, as these proteins facilitate carrier vesicle movement within cells. Rab 36 is ubiquitously expressed and primarily localizes to the Golgi membrane, where Rab 36 actively participates in protein trafficking. The gene encoding Rab 36 is situated in a critical region of chromosome 22, which is frequently deleted or involved in translocations associated with malignant rhabdoid tumors (MRTs), suggesting potential implications in tumorigenesis.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Rab 36 Antibody (379.2) References:

    1. Isolation of genes from the rhabdoid tumor deletion region in chromosome band 22q11.2.  |  Zhou, J., et al. 2000. Gene. 241: 133-41. PMID: 10607907
    2. Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation.  |  Sun, P., et al. 2003. J Biol Chem. 278: 4063-71. PMID: 12446704
    3. Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis.  |  Chen, T., et al. 2003. Biochem Biophys Res Commun. 303: 1114-20. PMID: 12684051
    4. Microarray analysis of temporal gene responses to ionizing radiation in two glioblastoma cell lines: up-regulation of DNA repair genes.  |  Otomo, T., et al. 2004. J Radiat Res. 45: 53-60. PMID: 15133290
    5. Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors.  |  Mori, T., et al. 1999. Biochem Biophys Res Commun. 254: 594-600. PMID: 9920784

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Rab 36 Antibody (379.2)

    sc-81916
    50 µg/0.5 ml
    $316.00

    Can sc-81916: Rab 36 (379.2) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: Trav11
    Thank you for your question. Yes, sc-81916: Rab 36 (379.2) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 5 out of 5 by from Good for Western BlotAntibody detects human Rab 36 in A-431 cell lysates by Western blot. -SCBT QC
    Date published: 2023-09-14
    Rated 5 out of 5 by from Tested for IF: very good stainingTested at 2 ug/ml in PFA/MeOH fixed/permeabilized primary cells. It works very well
    Date published: 2017-10-05
    Rated 5 out of 5 by from Worked great for IHC with paraffinWorked great for IHC with paraffin-embedded human tonsil tissue samples. -SCBT QC
    Date published: 2015-04-26
    Rated 5 out of 5 by from Good IF staining with paraformaldehydeGood IF staining with paraformaldehyde-fixed A-431 cells. -SCBT QC
    Date published: 2015-01-31
    Rated 5 out of 5 by from Single clean band in ASingle clean band in A-431 whole cell lysate. -SCBT QC
    Date published: 2013-05-12
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    Rab 36 Antibody (379.2) is rated 5.0 out of 5 by 5.
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