Rab 31 Antibody (4D12): sc-517069

Rab 31 Antibody (4D12) is a mouse monoclonal IgG2a kappa light chain antibody that detects the Rab 31 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 31 antibody (4D12) is available as the non-conjugated format. Rab 31, also known as RAB22B, is a 194 amino acid lipid-anchored protein that plays a crucial role in intracellular transport processes, particularly in the movement of proteins from the endoplasmic reticulum to the Golgi apparatus and ultimately to secretory vesicles. This transport is essential for maintaining cellular function and homeostasis, as proteins are delivered to their correct destinations within the cell. Additionally, Rab 31 is involved in endocytic pathways, highlighting its importance in both exocytosis and endocytosis. Rab 31 is predominantly expressed in the lung, brain, and heart, suggesting a significant role in the physiological processes of these vital organs. Anti-Rab 31 antibody (4D12) enables researchers to gain valuable insights into the mechanisms of protein transport and the functional implications of Rab proteins in various cellular contexts.

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Rab 31 Antibody (4D12) References:

1. Role of rRAB22b, an oligodendrocyte protein, in regulation of transport of vesicles from trans Golgi to endocytic compartments.  |  Rodriguez-Gabin, AG., et al. 2001. J Neurosci Res. 66: 1149-60. PMID: 11746448
2. Molecular cloning, bacterial expression and properties of Rab31 and Rab32.  |  Bao, X., et al. 2002. Eur J Biochem. 269: 259-71. PMID: 11784320
3. Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.  |  Lodhi, IJ., et al. 2007. Cell Metab. 5: 59-72. PMID: 17189207
4. Rab22B's role in trans-Golgi network membrane dynamics.  |  Ng, EL., et al. 2007. Biochem Biophys Res Commun. 361: 751-7. PMID: 17678623
5. Urokinase receptor splice variant uPAR-del4/5-associated gene expression in breast cancer: identification of rab31 as an independent prognostic factor.  |  Kotzsch, M., et al. 2008. Breast Cancer Res Treat. 111: 229-40. PMID: 17952591
6. Molecular cloning of two novel rab genes from human melanocytes.  |  Chen, D., et al. 1996. Gene. 174: 129-34. PMID: 8863739

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Rab 31 Antibody (4D12) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Rab 31 Antibody (4D12) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Rab 31 Antibody (4D12) Specifications

Alternate Product Name: Rab 31

Product Clone Name: 4D12

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 96-195

Epitope Target: Rab 31

Epitope Species: human

Product Reactivity/Detection: Rab 31

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Rab 31 Antibody (4D12): N/A