Date published: 2025-11-21

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Rab 20 Antibody (169E2W): sc-517618

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  • Rab 20 Antibody (169E2W) is a mouse monoclonal IgG2a Rab 20 antibody provided at 100 µg/ml
  • raised against recombinant Rab 20 of human origin
  • recommended for detection of Rab 20 of human origin by WB
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rab 20 Antibody (169E2W). This work is in progress.

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    Rab 20 Antibody (169E2W) is a mouse monoclonal IgG2a antibody that detects Rab 20 protein of human origin by western blotting (WB). Anti-Rab 20 antibody (169E2W) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important protein. Rab 20, also known as Ras-related protein Rab-20, is a 234 amino acid protein primarily localized to the Golgi apparatus, a critical site for protein processing and trafficking within the cell. The Golgi apparatus plays a vital role in modifying, sorting, and packaging proteins for secretion or delivery to other organelles, making Rab 20 essential for maintaining cellular function and homeostasis. Rab 20 belongs to the Rab subfamily of small GTPases, which are key regulators of vesicular transport, including both endocytosis and the biosynthetic pathway. Notably, Rab 20 is expressed in both normal and cancerous pancreatic tissue, where Rab 20 is implicated in apical endocytosis and recycling processes, potentially influencing the development of exocrine pancreatic adenocarcinomas. Anti-Rab 20 antibody (169E2W) enables researchers to gain insights into Rab 20′s role in cellular transport mechanisms and implications in pancreatic cancer biology.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Rab 20 Antibody (169E2W) References:

    1. The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily.  |  Pereira-Leal, JB. and Seabra, MC. 2000. J Mol Biol. 301: 1077-87. PMID: 10966806
    2. The Rab GTPase family.  |  Stenmark, H. and Olkkonen, VM. 2001. Genome Biol. 2: REVIEWS3007. PMID: 11387043
    3. Evolution of the Rab family of small GTP-binding proteins.  |  Pereira-Leal, JB. and Seabra, MC. 2001. J Mol Biol. 313: 889-901. PMID: 11697911
    4. Structural clues to Rab GTPase functional diversity.  |  Pfeffer, SR. 2005. J Biol Chem. 280: 15485-8. PMID: 15746102
    5. Characterization of human Rab20 overexpressed in exocrine pancreatic carcinoma.  |  Amillet, JM., et al. 2006. Hum Pathol. 37: 256-63. PMID: 16613320
    6. Identification of rab20 as a potential regulator of connexin 43 trafficking.  |  Das Sarma, J., et al. 2008. Cell Commun Adhes. 15: 65-74. PMID: 18649179
    7. Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression.  |  Lütcke, A., et al. 1994. J Cell Sci. 107 (Pt 12): 3437-48. PMID: 7706395
    8. Genetic mapping of Rab20 on mouse chromosome 8.  |  McMurtrie, EB., et al. 1997. Mamm Genome. 8: 291-2. PMID: 9096117

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Rab 20 Antibody (169E2W)

    sc-517618
    100 µg/ml
    $316.00