Date published: 2025-12-17

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(R)-Semixanthomegnin

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Application:
(R)-Semixanthomegnin is an antibacterial mycotoxin derivative
Purity:
≥97%
Molecular Weight:
288.25
Molecular Formula:
C15H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(R)-Semixanthomegnin, a naturally occurring compound derived from fungal sources, has garnered significant attention in scientific research due to its intriguing chemical structure and potential biological activities. This chemical exhibits diverse bioactive properties, including antimicrobial, antiviral, and anticancer effects. One of the notable mechanisms of action attributed to (R)-Semixanthomegnin is its ability to inhibit key enzymes involved in the biosynthesis of essential cellular components. For instance, research has shown that (R)-Semixanthomegnin can selectively target and inhibit the activity of enzymes such as DNA topoisomerases, which play crucial roles in DNA replication and transcription processes. Additionally, (R)-Semixanthomegnin has been investigated for its potential as a modulator of cellular signaling pathways, particularly those involved in inflammation, apoptosis, and cell cycle regulation. Moreover, studies have explored the chemical′s role as a lead compound in drug discovery efforts aimed at developing novel targets for various diseases, including infectious diseases and cancer. Overall, (R)-Semixanthomegnin represents a promising candidate for further research into its biological activities and potential applications in biomedical sciences, offering insights into novel drug targets and research strategies.


(R)-Semixanthomegnin References

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  2. Antibacterial phenolic components from Eriocaulon buergerianum.  |  Fang, JJ., et al. 2008. Phytochemistry. 69: 1279-86. PMID: 18191163
  3. Naphthopyranones--isolation, bioactivity, biosynthesis and synthesis.  |  Donner, CD. 2015. Nat Prod Rep. 32: 578-604. PMID: 25531639
  4. First asymmetric total synthesis of aspergillide D.  |  Jena, BK., et al. 2017. Org Biomol Chem. 15: 1863-1871. PMID: 28165093
  5. Review on Compounds Isolated from Eriocaulaceae Family and Evaluation of Biological Activities by Machine Learning.  |  Moreira, LLPF., et al. 2022. Molecules. 27: PMID: 36364014
  6. Omnipolyphilins A and B: Chlorinated Cyclotetrapeptides and Naphtho-α-pyranones from the Plant Nematode-Derived Fungus Polyphilus sieberi.  |  Wennrich, JP., et al. 2024. J Agric Food Chem. 72: 6998-7009. PMID: 38507729
  7. Pigments of Fungi. Part 70.* Total Synthesis of (R)-Semixanthomegnin and the X-Ray Crystal Structure of (±)-7-Chloro-10-methoxy-3-methyl-3, 4-dihydro-1 H-naphtho [2, 3-c] pyran-1, 6, 9-trione.  |  Cotterill, Ann S., et al. 2003. Australian journal of chemistry. 56.1: 49-57.
  8. Chemical analysis of Eriocaulon buergerianum and adulterating species by high-performance liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry.  |  Qiao, Xue, et al. 2012. ournal of pharmaceutical and biomedical analysis. 57: 133-142.
  9. Chemical constituents from capitula of Eriocaulon australe.  |  Xu, Q. L., et al. 2014. Zhong yao cai= Zhongyaocai= Journal of Chinese Medicinal Materials. 37.6: 992-995.
  10. A New Phthalide Derivative from the Mangrove-Derived Fungus Eupenicillium sp. HJ002.  |  Liao, Hai-Xia, et al. 2023. Chemistry of Natural Compounds. 59.3: 441-443.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-Semixanthomegnin, 500 µg

sc-396555
500 µg
$167.00

(R)-Semixanthomegnin, 1 mg

sc-396555A
1 mg
$280.00