(R,S)-N-Ethylnorcotinine (CAS 359435-41-9)
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(R,S)-N-Ethylnorcotinine functions as a potent inhibitor of cytochrome P450 enzymes. It acts by binding to the active site of the enzyme, thereby preventing the metabolism of nicotine and other substrates. This inhibition results in an increase in the plasma concentration of nicotine and its metabolites. At the molecular level, (R,S)-N-Ethylnorcotinine competes with nicotine for binding to the enzyme, leading to a decrease in the rate of nicotine metabolism. (R,S)-N-Ethylnorcotinine plays a role in elucidating the metabolic pathways of nicotine and understanding the interactions between nicotine and cytochrome P450 enzymes. Its mechanism of action involves interfering with the enzymatic conversion of nicotine.
(R,S)-N-Ethylnorcotinine (CAS 359435-41-9) References
- Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease. | Gao, J., et al. 2014. Bioorg Med Chem Lett. 24: 1472-8. PMID: 24581918
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R,S)-N-Ethylnorcotinine, 10 mg | sc-212640 | 10 mg | $367.00 | |||
(R,S)-N-Ethylnorcotinine, 25 mg | sc-212640A | 25 mg | $653.00 | |||
(R,S)-N-Ethylnorcotinine, 50 mg | sc-212640B | 50 mg | $1117.00 |