Molecular structure of (R,S)-Anatabine, CAS Number: 2743-90-0
(R,S)-Anatabine (CAS 2743-90-0)
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Alternate Names:
(±)-Anatabine
Application:
(R,S)-Anatabine is a nicotine metabolite
CAS Number:
2743-90-0
Molecular Weight:
160.21
Molecular Formula:
C10H12N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(R,S)-Anatabine is a nicotine metabolite. (R,S)-Anatabine is a colorless liquid compound comprising two pyridine rings connected by a methylene bridge. Its applications encompass organic synthesis, and chemical catalysis. Additionally, (R,S)-Anatabine serves as a potent antioxidant, safeguarding cells against oxidative harm. Notably, (R,S)-Anatabine acts as an inhibitor of the acetylcholinesterase enzyme involved in neurotransmitter release regulation.
(R,S)-Anatabine (CAS 2743-90-0) References
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- A novel validated procedure for the determination of nicotine, eight nicotine metabolites and two minor tobacco alkaloids in human plasma or urine by solid-phase extraction coupled with liquid chromatography-electrospray ionization-tandem mass spectrometry. | Miller, EI., et al. 2010. J Chromatogr B Analyt Technol Biomed Life Sci. 878: 725-37. PMID: 20097626
- Identification and quantification of nicotine biomarkers in human oral fluid from individuals receiving low-dose transdermal nicotine: a preliminary study. | Miller, EI., et al. 2010. J Anal Toxicol. 34: 357-66. PMID: 20822672
- Validation of a liquid chromatography-tandem mass spectrometry method for the detection of nicotine biomarkers in hair and an evaluation of wash procedures for removal of environmental nicotine. | Miller, EI., et al. 2011. J Anal Toxicol. 35: 321-32. PMID: 21740688
- Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry. | Vieira-Brock, PL., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 3465-74. PMID: 21963483
- Development and characterization of the α3β4α5 nicotinic receptor cellular membrane affinity chromatography column and its application for on line screening of plant extracts. | Ciesla, L., et al. 2016. J Chromatogr A. 1431: 138-144. PMID: 26774122
- Optimization of a Differential Ion Mobility Spectrometry-Tandem Mass Spectrometry Method for High-Throughput Analysis of Nicotine and Related Compounds: Application to Electronic Cigarette Refill Liquids. | Regueiro, J., et al. 2016. Anal Chem. 88: 6500-8. PMID: 27173877
- Cigarette smoke condensate may disturb immune function with apoptotic cell death by impairing function of organelles in alveolar macrophages. | Park, EJ., et al. 2018. Toxicol In Vitro. 52: 351-364. PMID: 30031032
- The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats. | Pentel, PR., et al. 2018. BMC Biotechnol. 18: 46. PMID: 30041697
- Recent advances in bio-affinity chromatography for screening bioactive compounds from natural products. | Guo, J., et al. 2019. J Pharm Biomed Anal. 165: 182-197. PMID: 30553109
- Tobacco and Pituri Use in Pregnancy: A Protocol for Measuring Maternal and Perinatal Exposure and Outcomes in Central Australian Aboriginal Women. | Ratsch, A., et al. 2019. Methods Protoc. 2: PMID: 31181680
- Determination of tobacco alkaloid enantiomers using reversed phase UPLC/MS/MS. | Ji, H., et al. 2019. Heliyon. 5: e01719. PMID: 31193304
- Development of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory Compounds. | Marescotti, D., et al. 2021. Front Pharmacol. 12: 639716. PMID: 33935729
- Evaluation of pharmacological activities and active components in Tremella aurantialba by instrumental and virtual analyses. | Yan, Y., et al. 2022. Front Nutr. 9: 1083581. PMID: 36570135
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AChRα5.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R,S)-Anatabine, 10 mg | sc-212639 | 10 mg | $275.00 |