Molecular structure of (R)-Prunasin, CAS Number: 99-18-3
(R)-Prunasin (CAS 99-18-3)
See product citations (1)
CAS Number:
99-18-3
Purity:
95%
Molecular Weight:
295.29
Molecular Formula:
C14H17NO6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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(R)-Prunasin is a cyanogenic glucoside present in species of the genera Prunus and Olinia, serving as the precursor to amygdalin, a bitter compound. It can undergo degradation by prunasin hydrolase and mandelonitrile lyase enzymes, resulting in the formation of hydrogen cyanide, glucose, and benzaldehyde. Furthermore, (R)-Prunasin exhibits inhibitory effects on plant growth. In addition, it has been reported to inhibit rat DNA polymerase β, an enzyme responsible for base excision repair essential for DNA maintenance and replication, with an IC50 value of 98 µM.
(R)-Prunasin (CAS 99-18-3) References
- Tissue Level Compartmentation of (R)-Amygdalin and Amygdalin Hydrolase Prevents Large-Scale Cyanogenesis in Undamaged Prunus Seeds. | Poulton, JE. and Li, CP. 1994. Plant Physiol. 104: 29-35. PMID: 12232058
- Utilization of Amygdalin during Seedling Development of Prunus serotina. | Swain, E. and Poulton, JE. 1994. Plant Physiol. 106: 437-445. PMID: 12232341
- Immunocytochemical Localization of Prunasin Hydrolase and Mandelonitrile Lyase in Stems and Leaves of Prunus serotina. | Swain, E. and Poulton, JE. 1994. Plant Physiol. 106: 1285-1291. PMID: 12232409
- Catabolism of Cyanogenic Glycosides by Purified Vicianin Hydrolase from Squirrel's Foot Fern (Davallia Trichomanoides Blume). | Lizotte, PA. and Poulton, JE. 1988. Plant Physiol. 86: 322-4. PMID: 16665903
- Facile Synthesis of Cyanogen Glycosides (R)-Prunasin, Linamarin and (S)-Heterodendrin. | Nakajima, N. and Ubukata, M. 1998. Biosci Biotechnol Biochem. 62: 453-8. PMID: 27315925
- Comparison of kinetic and molecular properties of two forms of amygdalin hydrolase from black cherry (Prunus serotina Ehrh.) seeds. | Kuroki, GW. and Poulton, JE. 1986. Arch Biochem Biophys. 247: 433-9. PMID: 3087290
- Cyanogenesis in tropical Prunus turneriana: characterisation, variation and response to low light. | Miller, RE., et al. 2004. Funct Plant Biol. 31: 491-503. PMID: 32688921
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-Prunasin, 2.5 mg | sc-208252 | 2.5 mg | $385.00 | |||
(R)-Prunasin, 5 mg | sc-208252A | 5 mg | $650.00 | |||
(R)-Prunasin, 10 mg | sc-208252B | 10 mg | $1220.00 |