(R)-(+)-HA-966 CAS: 123931-04-4
MF: C4H8N2O2
MW: 116.12
An antagonist/partial agonist at the glycine site of the NMDA receptor.

(R)-(+)-HA-966 (CAS 123931-04-4)

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Alternate Names: R(+)-3-Amino-1-hydroxy-2-pyrrolidinone
Application: (R)-(+)-HA-966 is an antagonist/partial agonist at the glycine site of the NMDA receptor
CAS Number: 123931-04-4
Purity: ≥98%
Molecular Weight: 116.12
Molecular Formula: C4H8N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

(R)-(+)-HA-966 has been reported to be a cell permeable antagonist and a partial agonist at the glycine site of the NMDA receptor. (R)-(+)-HA-966 is an inhibitor of NMDA and an activator of NMDA.

Physical State :
Solid
Solubility :
Soluble in water (100 mM).
Storage :
Desiccate at room temperature
Melting Point :
164-165° C
Boiling Point :
~258.6° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.59 (Predicted)
Optical Activity :
α20/D +112.2°, c = 1 in water; α22/D +103°, c = 1 in water
IC50 :
Glutamate NMDA receptor: IC50 = 12.5 µM (rat); Glutamate receptor subunit ζ 1: IC50 = 12.5 µM (rat)
Ki Data :
Rat: Ki= 2.5 µM; Glutamate receptor subunit ε 3: Ki= 2.5 µM (rat)
pK Values :
pKa: 7.19 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
6603720
MDL Number :
MFCD00078583
SMILES :
C1CN(C(=O)[[email protected]@H]1N)O

Download SDS (MSDS)

Certificate of Analysis

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