Date published: 2026-5-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

R-Palmitoyl-(2-methyl) Ethanolamide (CAS 179951-56-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
N-(2R-hydroxypropyl)-hexadecanamide
Application:
R-Palmitoyl-(2-methyl) Ethanolamide is a metabolically stable analog of palmitoyl ethanolamide
CAS Number:
179951-56-5
Molecular Weight:
313.5
Molecular Formula:
C19H39NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

R-Palmitoyl-(2-methyl) Ethanolamide, with the CAS number 179951-56-5, is a synthetic analog of the fatty acid amide family, specifically designed to probe the biological roles and mechanisms of N-acylethanolamines (NAEs). This compound is structurally characterized by a palmitic acid moiety linked to an ethanolamine group that contains a methyl substitution at the second carbon. This structural modification is crucial for research, as it provides insights into how slight changes in molecular structure can alter the interaction with cellular receptors and enzymes involved in lipid signaling pathways. In research settings, R-Palmitoyl-(2-methyl) Ethanolamide is utilized to study its affinity and efficacy towards cannabinoid receptors, which are part of a larger system influencing various cellular functions such as energy balance, mood regulation, and cellular stress responses. Additionally, this compound aids in examining the role of fatty acid amides in modulating the activity of these receptors, thereby influencing signal transduction pathways that govern physiological processes. By understanding the specific interactions and effects of this molecule within cellular systems, researchers aim to explain the broader roles of modified fatty acid amides in cellular signaling, potentially leading to novel insights into the modulation of lipid-derived mediators in cellular homeostasis.


R-Palmitoyl-(2-methyl) Ethanolamide (CAS 179951-56-5) References

  1. Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide.  |  Jonsson, KO., et al. 2001. Br J Pharmacol. 133: 1263-75. PMID: 11498512
  2. Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility.  |  Franklin, A., et al. 2003. J Neurosci. 23: 7767-75. PMID: 12944505
  3. Anti-inflammatory activity on compounds obtained from egg yolk, peanut oil, and soybean lecithin.  |  GANLEY, OH., et al. 1958. J Lab Clin Med. 51: 709-14. PMID: 13539486
  4. Human test models for bioequivalence of topical corticosteroids: a review.  |  Olsen, EA. 1992. Int J Dermatol. 31 Suppl 1: 9-13. PMID: 1428469
  5. Overview of the chemical families of fatty acid amide hydrolase and monoacylglycerol lipase inhibitors.  |  Vandevoorde, S. 2008. Curr Top Med Chem. 8: 247-67. PMID: 18289091
  6. Integrated transcriptomic and metabolomic analyses to characterize the anti-cancer effects of (-)-epigallocatechin-3-gallate in human colon cancer cells.  |  Zhang, Z., et al. 2020. Toxicol Appl Pharmacol. 401: 115100. PMID: 32512070
  7. Synthesis, Molecular Modeling and Biological Evaluation of Metabolically Stable Analogues of the Endogenous Fatty Acid Amide Palmitoylethanolamide.  |  D'Aloia, A., et al. 2020. Int J Mol Sci. 21: PMID: 33260658
  8. Dietary supplementation with inulin improves lactation performance and serum lipids by regulating the rumen microbiome and metabolome in dairy cows.  |  Wang, Y., et al. 2021. Anim Nutr. 7: 1189-1204. PMID: 34754961
  9. Screening of Endophytic Bacteria of Leucojum aestivum 'Gravety Giant' as a Potential Source of Alkaloids and as Antagonist to Some Plant Fungal Pathogens.  |  Munakata, Y., et al. 2022. Microorganisms. 10: PMID: 36296365

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

R-Palmitoyl-(2-methyl) Ethanolamide, 5 mg

sc-205483
5 mg
$28.00

R-Palmitoyl-(2-methyl) Ethanolamide, 10 mg

sc-205483A
10 mg
$53.00