(R)-(−)-N-3-Benzylnirvanol (CAS 790676-41-4)
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A potent and selective human CYP2C19 inhibitor. Derived from nirvanol, an alkaloid found in several plants, BNZ belongs to the alkylphenol family and shares similarities with naturally occurring nirvanol. In the field of inflammation research, studies have demonstrated that (R)-(−)-N-3-Benzylnirvanol effectively inhibits the production of pro-inflammatory cytokines. Although the precise mechanism of action of (R)-(−)-N-3-Benzylnirvanol is not yet fully elucidated, it is believed to modulate the activity of several enzymes and receptors, including cyclooxygenase-2, 5-lipoxygenase, and the serotonin receptor 5-HT2A. Additionally, (R)-(−)-N-3-Benzylnirvanol is thought to influence the expression of various genes involved in inflammation and cell proliferation, further enhancing its therapeutic potential.
(R)-(−)-N-3-Benzylnirvanol (CAS 790676-41-4) References
- Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors. | Suzuki, H., et al. 2004. Arch Biochem Biophys. 429: 1-15. PMID: 15288804
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-(−)-N-3-Benzylnirvanol, 50 mg | sc-208219 | 50 mg | $374.00 |