Molecular structure of (R)-(−)-3-Hydroxybutyric acid sodium salt, CAS Number: 13613-65-5
(R)-(−)-3-Hydroxybutyric acid sodium salt (CAS 13613-65-5)
See product citations (4)
Alternate Names:
(R)-(−)-3-Hydroxybutyric acid sodium salt is also known as D-(−)-3-Hydroxybutyric Acid Monosodium Salt.
Application:
(R)-(−)-3-Hydroxybutyric acid sodium salt is an optically active 3-hydroxybutyric acid and key intermediate in the biosynthesis and metabolism of fatty acids.
CAS Number:
13613-65-5
Purity:
≥95%
Molecular Weight:
126.09
Molecular Formula:
C4H7O3•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(R)-(−)-3-Hydroxybutyric acid sodium salt is extensively used in metabolic research, particularly in studies related to ketosis and energy metabolism. This compound is for investigating the role of ketone bodies in physiological energy regulation, especially during periods of low carbohydrate intake or high energy demand. Research involving (R)-(−)-3-Hydroxybutyric acid sodium salt focuses on its utilization as a major energy substrate by the brain and muscles, highlighting its potential in understanding metabolic health and efficiency. Additionally, it is employed in studies examining the effects of ketone bodies on cellular signaling and gene expression related to metabolism and stress responses.
(R)-(−)-3-Hydroxybutyric acid sodium salt (CAS 13613-65-5) References
- Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission. | Thio, LL., et al. 2000. Neurology. 54: 325-31. PMID: 10668691
- Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo. | Rho, JM., et al. 2002. Epilepsia. 43: 358-61. PMID: 11952765
- Enhanced production of D-(-)-3-hydroxybutyric acid by recombinant Escherichia coli. | Gao, HJ., et al. 2002. FEMS Microbiol Lett. 213: 59-65. PMID: 12127489
- Production of D-(--)-3-hydroxyalkanoic acid by recombinant Escherichia coli. | Zhao, K., et al. 2003. FEMS Microbiol Lett. 218: 59-64. PMID: 12583898
- Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. | Ide, T. 2010. Biosci Biotechnol Biochem. 74: 1578-82. PMID: 20699574
- HPLC determination of D-3-hydroxybutyric acid by derivatization with a benzofurazan reagent and fluorescent detection: application in the analysis of human plasma. | Cevasco, G., et al. 2014. Clin Chim Acta. 429: 90-5. PMID: 24315779
- A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome. | Benjamin, JS., et al. 2017. Proc Natl Acad Sci U S A. 114: 125-130. PMID: 27999180
- Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule. | Chriett, S., et al. 2019. Sci Rep. 9: 742. PMID: 30679586
- Effect of β-Hydroxybutyrate on Autophagy Dynamics During Severe Hypoglycemia and the Hypoglycemic Coma. | Torres-Esquivel, C., et al. 2020. Front Cell Neurosci. 14: 547215. PMID: 33173467
- RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes. | Ruppert, PM., et al. 2021. Life Sci Alliance. 4: PMID: 34407998
- Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine. | Terranova, CJ., et al. 2021. Cell Rep. 37: 110044. PMID: 34818540
- Serological and structural features of Hafnia alvei lipopolysaccharides containing D-3-hydroxybutyric acid. | Romanowska, A., et al. 1994. FEMS Immunol Med Microbiol. 8: 83-8. PMID: 8156055
- The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children. | Freeman, JM., et al. 1998. Pediatrics. 102: 1358-63. PMID: 9832569
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-(−)-3-Hydroxybutyric acid sodium salt, 1 g | sc-229050 | 1 g | $133.00 | |||
(R)-(−)-3-Hydroxybutyric acid sodium salt, 5 g | sc-229050A | 5 g | $360.00 | |||
(R)-(−)-3-Hydroxybutyric acid sodium salt, 10 g | sc-229050B | 10 g | $625.00 | |||
(R)-(−)-3-Hydroxybutyric acid sodium salt, 25 g | sc-229050C | 25 g | $1200.00 |