Molecular structure of (R)-(+)-m-Nitrobiphenyline oxalate, CAS Number: 945618-97-3
(R)-(+)-m-Nitrobiphenyline oxalate (CAS 945618-97-3)
See product citations (1)
Application:
(R)-(+)-m-Nitrobiphenyline oxalate is an α2C-AR agonist which inhibits cAMP accumulation
CAS Number:
945618-97-3
Purity:
≥99%
Molecular Weight:
401.37
Molecular Formula:
C17H17N3O3•C2H2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
(R)-(+)-m-Nitrobiphenyline oxalate is an alpha2C-AR (adrenoceptor) agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM).It behaves as an antagonist at alpha2A-AR and alpha2B-AR (pKb = 7.11 and 6.07 respectively). (R)-(+)-m-Nitrobiphenyline oxalate, or (R)-(+)-m-NBO, is a valuable research compound with a molecular formula of C17H17N3O3.C2H2O4 and a molecular weight of 401.38. It is typically available in a purity of 95%.
(R)-(+)-m-Nitrobiphenyline oxalate (CAS 945618-97-3) References
- Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist. | Crassous, PA., et al. 2007. J Med Chem. 50: 3964-8. PMID: 17630725
- Alpha2-adrenergic receptor activation regulates cortical interneuron migration. | Riccio, O., et al. 2012. Eur J Neurosci. 36: 2879-87. PMID: 22805283
- Angiotensin AT1 - α2C-Adrenoceptor Interaction Disturbs α2A-auto-Inhibition of Catecholamine Release in Hypertensive Rats. | Berg, T. 2013. Front Neurol. 4: 70. PMID: 23772221
- Vasoactivity and Vasoconstriction Changes in Cattle Related to Time off Toxic Endophyte-Infected Tall Fescue. | Klotz, JL., et al. 2016. Toxins (Basel). 8: PMID: 27669299
Inhibitor of:
alpha2A-AR, and alpha2B-AR.Activator of:
alpha2C-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-(+)-m-Nitrobiphenyline oxalate, 10 mg | sc-204226 | 10 mg | $250.00 | |||
| US: Only available in the US | ||||||
(R)-(+)-m-Nitrobiphenyline oxalate, 50 mg | sc-204226A | 50 mg | $850.00 | |||
| US: Only available in the US | ||||||