(R)-Citalopram OxalateA derivative of Citalopram

(R)-Citalopram Oxalate (CAS 219861-53-7)

(R)-Citalopram Oxalate | CAS 219861-53-7 is rated 5.0 out of 5 by 1.
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Application: A derivative of Citalopram
CAS Number: 219861-53-7
Molecular Weight: 414.43
Molecular Formula: C22H23FN2O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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(R)-Citalopram Oxalate is a derivative of Citalopram (sc-201123). Citalopram is a selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavor.


References

1. Torres, G.E., et al. 2003. Nat. Rev. Neurosci. 4: 13-25. PMID: 12511858
2. Palotás, A., et al. 2004. Neurochem. Res. 29: 1563-1570. PMID: 15260135
3. Neubauer, H.A., et al. 2006. Mol. Pharmacol. 69: 1242-1250. PMID: 16434615
4. Gabriel, J.P., et al. 2009. J. Neurosci. 29: 10387-10395. PMID: 19692613

Physical State :
Solid
Solubility :
Soluble in methanol.
Storage :
Store at -20° C
Melting Point :
153-155° C
Optical Activity :
α20/D -10.9°, c = 0.5 in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
146571
MDL Number :
MFCD06407825
SMILES :
OC(=O)C(O)=O.CN(C)CCC[C@@]1(OCC2=CC(=CC=C12)C#N)C1=CC=C(F)C=C1

Download SDS (MSDS)

Certificate of Analysis

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(R)-Citalopram Oxalate  Product Citations

See how others have used (R)-Citalopram Oxalate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26338061  Krasulova, K. et al. 2016. Xenobiotica. 46: 315-24.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Citalopram was reported in many publications Citalopram was reported in many publications as a derivative of Citalopram, a selective serotonin reuptake inhibitor. -SCBT Publication Review
Date published: 2015-04-15
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