Molecular structure of (R)-Citalopram Oxalate, CAS Number: 219861-53-7
(R)-Citalopram Oxalate (CAS 219861-53-7)
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Application:
(R)-Citalopram Oxalate is a derivative of Citalopram
CAS Number:
219861-53-7
Molecular Weight:
414.43
Molecular Formula:
C22H23FN2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(R)-Citalopram Oxalate is a derivative of Citalopram (sc-201123). Citalopram is a selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavor.
(R)-Citalopram Oxalate (CAS 219861-53-7) References
- Plasma membrane monoamine transporters: structure, regulation and function. | Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
- R-citalopram attenuates anxiolytic effects of escitalopram in a rat ultrasonic vocalisation model. | Sánchez, C. 2003. Eur J Pharmacol. 464: 155-8. PMID: 12620508
- Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities. | Sánchez, C., et al. 2003. Psychopharmacology (Berl). 167: 353-62. PMID: 12719960
- The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats. | Mørk, A., et al. 2003. Neuropharmacology. 45: 167-73. PMID: 12842122
- Stereospecific determination of citalopram and desmethylcitalopram by capillary electrophoresis and liquid-phase microextraction. | Andersen, S., et al. 2003. J Pharm Biomed Anal. 33: 263-73. PMID: 12972091
- R-citalopram inhibits functional and 5-HTP-evoked behavioural responses to the SSRI, escitalopram. | Sánchez, C. and Kreilgaard, M. 2004. Pharmacol Biochem Behav. 77: 391-8. PMID: 14751469
- The effect of citalopram on gene expression profile of Alzheimer lymphocytes. | Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
- Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study. | Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
- Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms. | Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
- Validated Densitometric TLC-Method for the Simultaneous Analysis of (R)- and (S)-Citalopram and its Related Substances Using Macrocyclic Antibiotic as a Chiral Selector: Application to the Determination of Enantiomeric Purity of Escitalopram. | Soliman, SM. 2012. Int J Biomed Sci. 8: 40-50. PMID: 23675256
- The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse. | Jacobsen, JP., et al. 2014. Psychopharmacology (Berl). 231: 4527-40. PMID: 24810106
- Effects of escitalopram, R-citalopram, and reboxetine on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration. | Dong, C., et al. 2016. Pharmacol Biochem Behav. 144: 7-12. PMID: 26892759
- Investigation of the degradation and in-situ amorphization of the enantiomeric drug escitalopram oxalate during Fused Deposition Modeling (FDM) 3D printing. | Hoffmann, L., et al. 2023. Eur J Pharm Sci. 185: 106423. PMID: 36918059
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-Citalopram Oxalate, 5 mg | sc-219751 | 5 mg | $340.00 | |||
(R)-Citalopram Oxalate, 25 mg | sc-219751A | 25 mg | $1440.00 | |||
(R)-Citalopram Oxalate, 50 mg | sc-219751B | 50 mg | $2400.00 | |||
(R)-Citalopram Oxalate, 100 mg | sc-219751C | 100 mg | $4500.00 |