Date published: 2026-2-6

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(R)-(−)-α-Phellandrene (CAS 4221-98-1)

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Alternate Names:
(R)-5-Isopropyl-2-methyl-1,3-cyclohexadiene; (R)-(−)-alpha-Phellandrene
CAS Number:
4221-98-1
Molecular Weight:
136.23
Molecular Formula:
C10H16
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(R)-(−)-α-Phellandrene is a naturally occurring monoterpene, used extensively in research related to natural products chemistry and ecological interactions. In studies on plant-insect interactions, this compound is of interest due to its presence in the essential oils of certain plants that can act as attractants or repellents to insects. Research involving (R)-(−)-α-Phellandrene also delves into the area of chemical ecology, where it may play a role in plant defense mechanisms against herbivores. Furthermore, it is used in olfactory research to understand the perception and physiological responses of organisms to this specific terpene. In the field of analytical chemistry, (R)-(−)-α-Phellandrene serves as a reference standard in chromatographic analyses for the identification and quantification of terpenes in complex biological mixtures.


(R)-(−)-α-Phellandrene (CAS 4221-98-1) References

  1. Simple chiral diene ligands provide high enantioselectivities in transition-metal-catalyzed conjugate addition reactions.  |  Okamoto, K., et al. 2008. Org Lett. 10: 4387-9. PMID: 18771267
  2. Selectivity in the electron transfer catalyzed Diels-Alder reaction of (R)-alpha-phellandrene and 4-methoxystyrene.  |  Sevov, CS. and Wiest, O. 2008. J Org Chem. 73: 7909-15. PMID: 18785777
  3. Biotransformation of (-)-(R)-α-phellandrene: antimicrobial activity of its major metabolite.  |  İşcan, G., et al. 2012. Chem Biodivers. 9: 1525-32. PMID: 22899613
  4. Essential Oils of Echinophora lamondiana (Apiales: Umbelliferae): A Relationship Between Chemical Profile and Biting Deterrence and Larvicidal Activity Against Mosquitoes (Diptera: Culicidae).  |  Ali, A., et al. 2015. J Med Entomol. 52: 93-100. PMID: 26336285
  5. The Flower Essential Oil of Dalea mutisii Kunth (Fabaceae) from Ecuador: Chemical, Enantioselective, and Olfactometric Analyses.  |  Gilardoni, G., et al. 2020. Plants (Basel). 9: PMID: 33096831
  6. RIFM fragrance ingredient safety assessment, (-)-(R)-α-phellandrene, CAS Registry Number 4221-98-1.  |  Api, AM., et al. 2022. Food Chem Toxicol. 161 Suppl 1: 112912. PMID: 35278499
  7. Intrazeolite photo-oxygenation of (R)-(–)-α-phellandrene  |  Manolis Stratakis* and Nikoletta Sofikiti. 2002,. J. Chem. Research (S),. 374–375.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-(−)-α-Phellandrene, 5 ml

sc-250855
5 ml
$254.00

(R)-(−)-α-Phellandrene, 25 ml

sc-250855A
25 ml
$657.00