Date published: 2025-12-5

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(R)-(-)-3-Quinuclidinol (CAS 25333-42-0)

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Alternate Names:
(3R)-1-Azabicyclo[2.2.2]octan-3-ol; R-(-)-Azabicyclo[2.2.2]octane-3-ol; (R)-3-Quinuclidol; (R)-3-Hydroxyquinuclidine
Application:
(R)-(−)-3-Quinuclidinol is a synthon used for the preparation of cholinergic receptor ligands
CAS Number:
25333-42-0
Molecular Weight:
127.18
Molecular Formula:
C7H13NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Synthon for preparation of cholinergic receptor ligands and anesthetics. Hypotensive.


(R)-(-)-3-Quinuclidinol (CAS 25333-42-0) References

  1. Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk.  |  Lockridge, O. and Masson, P. 2000. Neurotoxicology. 21: 113-26. PMID: 10794391
  2. Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.  |  Kovarik, Z., et al. 2003. Biochem J. 373: 33-40. PMID: 12665427
  3. Production of (R)-3-quinuclidinol by E. coli biocatalysts possessing NADH-dependent 3-quinuclidinone reductase (QNR or bacC) from Microbacterium luteolum and Leifsonia alcohol dehydrogenase (LSADH).  |  Isotani, K., et al. 2012. Int J Mol Sci. 13: 13542-53. PMID: 23202966
  4. Enzymatic resolution and cholinergic properties of (+/-)3-quinuclidinol derivatives.  |  Rehavi, M., et al. 1977. Life Sci. 21: 1293-302. PMID: 927030
  5. Fungi mediated production and practical purification of (R)-(−)-3-quinuclidinol  |  Kolet, S. P., Jadhav, D. D., Priyadarshini, B., Swarge, B. N., & Thulasiram, H. V. 2014. Tetrahedron letters. 55(43): 5911-5914.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-(-)-3-Quinuclidinol, 1 g

sc-219718
1 g
$270.00
US: Only available in the US