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(R)-2-Hydroxybutyric acid (CAS 20016-85-7)

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Application:
(R)-2-Hydroxybutyric acid is a chiral building block
CAS Number:
20016-85-7
Molecular Weight:
104.10
Molecular Formula:
C4H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(R)-2-Hydroxybutyric acid, also known as (R)-2-hydroxybutanoic acid, is a chiral molecule characterized by its specific configuration at the second carbon atom, which bears a hydroxyl group (-OH) in the R-configuration. This organic compound belongs to the class of hydroxy acids, a category of molecules that feature both a hydroxyl group and a carboxylic acid group (-COOH) within their structures. As a result, (R)-2-Hydroxybutyric acid exhibits unique chemical properties, such as the ability to participate in various biochemical reactions, including esterification and dehydration. In research applications, this compound is particularly noteworthy for its role in stereochemical studies and enantioselective synthesis. Its distinct stereochemistry makes it an important model compound in the investigation of chiral recognition processes and the development of chiral catalysts.


(R)-2-Hydroxybutyric acid (CAS 20016-85-7) References

  1. Efficient conversion of 1,2-butanediol to (R)-2-hydroxybutyric acid using whole cells of Gluconobacter oxydans.  |  Gao, C., et al. 2012. Bioresour Technol. 115: 75-8. PMID: 22126977
  2. Synthesis and enantioselectivity of the enantiomers of PG9 and SM21, new potent analgesic and cognition-enhancing drugs.  |  Romanelli, MN., et al. 1996. Chirality. 8: 225-33. PMID: 8777145
  3. Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent.  |  Romanelli, MN., et al. 1996. Chirality. 8: 579-84. PMID: 9025257

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-2-Hydroxybutyric acid, 250 mg

sc-253419
250 mg
$218.00

(R)-2-Hydroxybutyric acid, 1 g

sc-253419A
1 g
$339.00

Hi, Can you tell me the % purity and enantiomeric excess of this product? Thanks!

Asked by: CharlesN
This item is synthesized chemically. The enantiomeric purity is 98%
Answered by: Technical Service
Date published: 2024-05-07

Do you offer a version of this product that is C13 isotope labeled (U13C (R)-2-hydroxybutyric acid)?

Asked by: CharlesN
Thank you for your question. At this time this is the only (R)-2-Hydroxybutyric acid we offer .
Answered by: BlakeJ
Date published: 2024-03-28
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Rated 5 out of 5 by from GaoGao, C. et al. (PubMed 22126977) presented the efficient conversion of 1,2-butanediol to (R)-2-hydroxybutyric acid using whole cells of Gluconobacter oxydans. -SCBT Publication Review
Date published: 2015-01-05
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(R)-2-Hydroxybutyric acid is rated 5.0 out of 5 by 1.
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