Molecular structure of R-(−)-O-Desmethyl Venlafaxine, CAS Number: 142761-11-3
R-(−)-O-Desmethyl Venlafaxine (CAS 142761-11-3)
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Alternate Names:
R)-(−)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (−)-O-Desmethylvenlafaxine; (R)-(−)-O-Desmethylvenlafaxine;
Application:
R-(−)-O-Desmethyl Venlafaxine is a venlafaxine metabolite
CAS Number:
142761-11-3
Molecular Weight:
263.38
Molecular Formula:
C16H25NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
R-(−)-O-Desmethyl Venlafaxine is a metabolite of R-Venlafaxine (sc-208209), a selective serotonin noradrenaline reuptake inhibitor. This bicyclic molecule facilitates neurotransmission by preventing presynaptic reuptake, resulting in a higher concentration of neurotransmitters located within the synapse. It is known that the neurotransmitters most effected by this inhibitor are norepinephrine and serotonin, which weakly suppress dopamine at high concentrations. Furthermore, studies show that R-(−)-O-Desmethyl Venlafaxine can be seperated from Venlafaxine using LC-MS/MS in rat plasma.
R-(−)-O-Desmethyl Venlafaxine (CAS 142761-11-3) References
- Simultaneous determination of venlafaxine and its main active metabolite O-desmethyl venlafaxine in rat plasma by LC-MS/MS. | Shah, GR., et al. 2009. Anal Sci. 25: 1207-10. PMID: 19822964
- Aluminized surface to improve solar light absorption in open reactors: Application for micropollutants removal in effluents from municipal wastewater treatment plants. | Costa, EP., et al. 2021. Sci Total Environ. 755: 142624. PMID: 33045600
- Venlafaxine. A review of its pharmacology and therapeutic potential in depression. | Holliday, SM. and Benfield, P. 1995. Drugs. 49: 280-94. PMID: 7729333
- Venlafaxine: a new antidepressant drug. | Holdcroft, C. 1994. Nurse Pract. 19: 21. PMID: 7816367
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
R-(−)-O-Desmethyl Venlafaxine, 5 mg | sc-208198 | 5 mg | $380.00 |