Date published: 2026-4-29

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Quininone (CAS 84-31-1)

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Alternate Names:
(8α)-6′-Methoxy-cinchonan-9-one; ICQ 15
CAS Number:
84-31-1
Molecular Weight:
322.40
Molecular Formula:
C20H22N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Quinone functions as an electron carrier in various redox reactions within experimental applications. It acts as a coenzyme in biological systems, participating in electron transfer processes. Quinone′s mechanism of action involves accepting and donating electrons, thereby facilitating the transfer of energy within cellular respiration and photosynthesis. At the molecular level, it interacts with various enzymes and proteins to mediate electron transport chains, playing a role in the generation of adenosine triphosphate (ATP) in cells. Its involvement in redox reactions allows for the conversion of chemical energy into a form that can be utilized by cells for various metabolic processes.


Quininone (CAS 84-31-1) References

  1. Nuclear overexpression of NADH:cytochrome b5 reductase activity increases the cytotoxicity of mitomycin C (MC) and the total number of MC-DNA adducts in Chinese hamster ovary cells.  |  Holtz, KM., et al. 2003. J Biol Chem. 278: 5029-34. PMID: 12424239
  2. Microbiological reduction of quininone to quinidine.  |  Ray, L., et al. 1983. Appl Environ Microbiol. 45: 1935-6. PMID: 16346323
  3. Radioimmunoassay for the quantitative determination of quinine in cultured plant tissues.  |  Robins, RJ., et al. 1984. Planta Med. 50: 235-8. PMID: 17340302
  4. Rabe rest in peace: confirmation of the rabe-kindler conversion of D-quinotoxine into quinine: experimental affirmation of the Woodward-Doering formal total synthesis of quinine.  |  Smith, AC. and Williams, RM. 2008. Angew Chem Int Ed Engl. 47: 1736-40. PMID: 18236503
  5. Bioconversion of quininone to quinidine by resting cells of Hansenula anomala var. schneggii.  |  Ray, L. and Majumdar, SK. 1991. Indian J Exp Biol. 29: 282-3. PMID: 1874545
  6. Ground and excited electronic states of quininone-containing Re(I)-based rectangles: a comprehensive study of their preparation, electrochemistry, and photophysics.  |  Bhattacharya, D., et al. 2009. Inorg Chem. 48: 3731-42. PMID: 19309160
  7. Chemistry of bridged lactams and related heterocycles.  |  Szostak, M. and Aubé, J. 2013. Chem Rev. 113: 5701-65. PMID: 24490625
  8. Addition of H-phosphonates to quinine-derived carbonyl compounds. An unexpected C9 phosphonate-phosphate rearrangement and tandem intramolecular piperidine elimination.  |  Górecki, L., et al. 2014. Beilstein J Org Chem. 10: 883-9. PMID: 24778744
  9. Novel Ionophores Active against La Crosse Virus Identified through Rapid Antiviral Screening.  |  Sandler, ZJ., et al. 2020. Antimicrob Agents Chemother. 64: PMID: 32284379
  10. Effect of Medium pH and Light on Quinidine Production in Cinchona calisaya Wedd. Endophytic Fungi.  |  Rahmawati, I., et al. 2021. Turk J Pharm Sci. 18: 124-132. PMID: 33900523
  11. Characterization of an Endophytic Strain Talaromyces assiutensis, CPEF04 With Evaluation of Production Medium for Extracellular Red Pigments Having Antimicrobial and Anticancer Properties.  |  Mishra, RC., et al. 2021. Front Microbiol. 12: 665702. PMID: 34421835
  12. The isolation and identification of quininone from Cinchona ledgeriana.  |  Crooks, PA. and Robinson, B. 1970. J Pharm Pharmacol. 22: 469-70. PMID: 4396117
  13. Analysis of Cinchona alkaloids by high-performance liquid chromatography. Application to the analysis of quinidine gluconate and quinidine sulfate and their dosage forms.  |  Smith, E. 1984. J Chromatogr. 299: 233-44. PMID: 6490780

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Quininone, 250 mg

sc-476983
250 mg
$270.00

Quininone, 2.5 g

sc-476983A
2.5 g
$3060.00