Date published: 2025-10-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

Quinine bisulfate (CAS 549-56-4)

5.0(1)
Write a reviewAsk a question

Alternate Names:
Quinine hydrogen sulfate; Quinine hydrogen sulphate; Quinine sulfate
CAS Number:
549-56-4
Molecular Weight:
746.92
Molecular Formula:
2C20H24N2O2•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Quinine sulfate is a compound that functions as a bitter-tasting alkaloid. It acts as a blood schizonticide. Its mechanism of action involves interfering with the parasite′s ability to digest hemoglobin, leading to the accumulation of toxic heme and subsequent death of the parasite. Quinine sulfate also disrupts the parasite′s ability to break down glucose, leading to a decrease in energy production and ultimately causing the death of the parasite. Quinine sulfate inhibits the nucleic acid synthesis of the parasite, further contributing to its antimalarial activity.


Quinine bisulfate (CAS 549-56-4) References

  1. Expedient liquid chromatographic method with fluorescence detection for montelukast sodium in micro-samples of plasma.  |  Al-Rawithi, S., et al. 2001. J Chromatogr B Biomed Sci Appl. 754: 527-31. PMID: 11339297
  2. [Considerations on a case of acute poisoning by quinine bisulfate in massive doses, for the purpose of suicide].  |  POPPI, A. and GASPERINI, G. 1961. Riforma Med. 75: 1100-6. PMID: 14487997
  3. Reevaluation of absolute luminescence quantum yields of standard solutions using a spectrometer with an integrating sphere and a back-thinned CCD detector.  |  Suzuki, K., et al. 2009. Phys Chem Chem Phys. 11: 9850-60. PMID: 19851565
  4. Calibration of a microspectrofluorophotometer in absolute units of radiation.  |  Corliss, DA., et al. 1980. Appl Opt. 19: 3290-4. PMID: 20234609
  5. Pamaquine naphthoate, quinacrine hydrochloride, and quinine bisulfate as curative agents in Plasmodium cathemerium infections of the duck.  |  WALKER, HA., et al. 1946. Fed Proc. 5: 210. PMID: 21064461
  6. Photochemical properties of UV Filter molecules of the human eye.  |  Tsentalovich, YP., et al. 2011. Invest Ophthalmol Vis Sci. 52: 7687-96. PMID: 21873681
  7. A direct liquid chromatographic quantitation of ciprofloxacin in microsamples of plasma with fluorometric detection.  |  el-Yazigi, A. and al-Rawithy, S. 1990. Ther Drug Monit. 12: 378-81. PMID: 2396312
  8. High Solid Fluorescence of a Pyrazoline Derivative through Hydrogen Bonding.  |  Zhang, L., et al. 2017. Molecules. 22: PMID: 28777332
  9. Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging.  |  Atabaev, TS., et al. 2018. J Funct Biomater. 9: PMID: 29783645
  10. Measurements of Absolute Values in Biochemical Fluorescence Spectroscopy.  |  Chen, RF. 1972. J Res Natl Bur Stand A Phys Chem. 76A: 593-606. PMID: 34565885
  11. The fluorescence excitation spectrum of quinine bisulfate.  |  Gill, JE. 1969. Photochem Photobiol. 9: 313-22. PMID: 5771414
  12. Determination of acrolein in urine by liquid chromatography and fluorescence detection of its quinoline derivative.  |  al-Rawithi, S., et al. 1993. Pharm Res. 10: 1587-90. PMID: 8290470
  13. Direct liquid chromatographic micro-measurement of tamoxifen in plasma of cancer patients.  |  El-Yazigi, A. and Legayada, E. 1997. J Chromatogr B Biomed Sci Appl. 691: 457-62. PMID: 9174284

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Quinine bisulfate, 50 mg

sc-280050
50 mg
$20.00

Quinine bisulfate, 1 g

sc-280050A
1 g
$46.00

Can this use as a reference standard for check fluorescence

Asked by: Anonymous
Thank you for contacting Santa Cruz Biotechnology. Our references show that it is possible to use for this purpose but we have not validated .
Answered by: BlakeJ
Date published: 2024-07-17
  • y_2025, m_10, d_14, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_280050, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 101ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Works GreatThe product worked well for our fluorescence lab. Much more soluble than Quinine Sulfate.
Date published: 2022-04-04
  • y_2025, m_10, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_280050, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
Quinine bisulfate is rated 5.0 out of 5 by 1.
  • y_2025, m_10, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_280050, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 119ms
  • REVIEWS, PRODUCT