Date published: 2025-12-5

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Quinacrine mustard dihydrochloride (CAS 4213-45-0)

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Alternate Names:
Atabrine mustard dihydrochloride
Application:
Quinacrine mustard dihydrochloride is a fluorescent probe
CAS Number:
4213-45-0
Purity:
≥90%
Molecular Weight:
541.77
Molecular Formula:
C23H28Cl3N3O•2HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Quinacrine mustard dihydrochloride is a fluorescent probe for labeling chromosomal DNA. Also used in measurement of sequence specificity with Taq DNA polymerase. Quinacrine mustard dihydrochloride, an alkylating agent, is a compound derived from mustard gas. Its application spans various research areas, including investigating DNA damage, oxidative stress, inflammation, and gene expression.


Quinacrine mustard dihydrochloride (CAS 4213-45-0) References

  1. Use of [8-3H]guanine-labeled deoxyribonucleic acid to study alkylating agent reaction kinetics and stability.  |  Mattes, WB. 1992. Anal Biochem. 206: 161-7. PMID: 1280918
  2. Cytogenetic assays of chemical clastogens using mammalian cells in culture.  |  Hsu, TC., et al. 1977. Mutat Res. 45: 233-47. PMID: 339065
  3. DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.  |  Mattes, WB., et al. 1986. Nucleic Acids Res. 14: 2971-87. PMID: 3960738
  4. Interaction of quinacrine mustard with calf thymus histone fractions.  |  Selander, RK. and De la Chapelle, A. 1973. Biochem J. 131: 757-64. PMID: 4737323
  5. Y-fluorescence of interphase nuclei, especially circulating lymphocytes.  |  Polani, PE. and Mutton, DE. 1971. Br Med J. 1: 138-42. PMID: 5539419
  6. Microfluorometric investigations of chromatin structure. I. Evaluation of nine DNA-specific fluorochromes as probes of chromatin organization.  |  Cowden, RR. and Curtis, SK. 1981. Histochemistry. 72: 11-23. PMID: 6169690
  7. Interaction of chromosomal stains with DNA. An electrofluorescence study.  |  Jennings, BR. and Ridler, PJ. 1983. Biophys Struct Mech. 10: 71-9. PMID: 6193819
  8. A simple fluorescence staining technique for the differentiation of human tissue transplanted into nude mice.  |  Müller, HJ. 1976. Stain Technol. 51: 287-91. PMID: 64003
  9. Detergent solubilization and affinity purification of a local anesthetic binding protein from mammalian axonal membranes.  |  Greenberg, M. and Tsong, TY. 1984. J Biol Chem. 259: 13241-5. PMID: 6490653
  10. Localization of the beta-globin gene by chromosomal in situ hybridization.  |  Morton, CC., et al. 1984. Am J Hum Genet. 36: 576-85. PMID: 6587773
  11. Comparison of 6-thioguanine-resistant mutation and sister chromatid exchanges in Chinese hamster V79 cells with forty chemical and physical agents.  |  Nishi, Y., et al. 1984. Cancer Res. 44: 3270-9. PMID: 6744262
  12. Quinacrine mustard and nucleolar organizer region heteromorphisms in twins.  |  Morton, CC., et al. 1981. Acta Genet Med Gemellol (Roma). 30: 39-49. PMID: 7199799
  13. Cytological identification of sex in pig embryos at indifferent gonadal stages.  |  Pelliniemi, LJ. and Salonius, AL. 1976. Acta Anat (Basel). 95: 558-64. PMID: 970092

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Quinacrine mustard dihydrochloride, 5 mg

sc-215770
5 mg
$116.00

Quinacrine mustard dihydrochloride, 25 mg

sc-215770A
25 mg
$220.00

Hi! I am from Canada - Montreal University Health Center (MUHC), Cytogenetics laboratory and I would like to know if you have CAS# 4213-45-0 in stock? If so, what is the ETA and is it possible to have a quotation for 3 x 5mg bottles please? Thank you!

Asked by: Annie Lemay
Thank you for your question. For a price quote and ship date please email scbt@scbt.com
Answered by: BlakeJ
Date published: 2024-04-22
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Rated 5 out of 5 by from Several publications cite the use of QuinacrineSeveral publications cite the use of Quinacrine mustard, a fluorescent probe, to stain chromosomal DNA. -SCBT Publication Review
Date published: 2015-01-04
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Quinacrine mustard dihydrochloride is rated 5.0 out of 5 by 1.
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