Quetiapine-d8 Fumarate (CAS 1185247-12-4)

Quetiapine-d8 fumarate, a deuterated version of quetiapine, serves primarily in the realm of research, particularly in pharmacokinetic and metabolic studies. The introduction of deuterium atoms into the quetiapine molecule enhances its analytical detectability and stability, allowing for more precise measurement of its interaction and degradation pathways. This compound is especially valuable in mass spectrometry, where its unique isotopic pattern facilitates clearer identification and quantification of quetiapine and its metabolites in complex biological matrices. Moreover, quetiapine-d8 fumarate aids in elucidating the pharmacodynamics of quetiapine by serving as an internal standard, thus ensuring accuracy and reproducibility in experiments focused on its mechanism of action at various neurotransmitter systems. Its role in research extends to the exploration of its binding affinities and functional responses in neurotransmission, which are for understanding its modulation of neurotransmitter pathways. This makes it an essential tool for scientific studies aiming to map out the biochemical landscape influenced by quetiapine.