Date published: 2025-9-5

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Quercetin (CAS 117-39-5)

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Alternate Names:
Meletin; Sophoretin; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
Application:
Quercetin is a PI 3-kinase inhibitor, GPR30 activator, and apoptosis inducer
CAS Number:
117-39-5
Purity:
≥95%
Molecular Weight:
302.24
Molecular Formula:
C15H10O7
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Quercetin, one of the main flavonoids that exists in galangal (Zingiberaceae), is a hydroxylated flavanoid that may act to cause potent reversible inhibition of fatty-acid synthase. It possesses potential antiinflammatory properties. Quercetin also inhibits Trk (tyrosine protein kinase), phospholipase A2, PDE (phosphodiesterases), mitochondrial ATPase, PI 3-kinase and PKC (protein kinase C). It has been reported that the competitive inhibition of FASN by quercetin leads to apoptotic cell death which results in inhibition of cell proliferation. Quercetin also behaves as a GPR30 activator and calcium channel protein inhibitor.


Quercetin (CAS 117-39-5) References

  1. Presence of fatty acid synthase inhibitors in the rhizome of Alpinia officinarum hance.  |  Li, BH. and Tian, WX. 2003. J Enzyme Inhib Med Chem. 18: 349-56. PMID: 14567550
  2. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?  |  Lupu, R. and Menendez, JA. 2006. Curr Pharm Biotechnol. 7: 483-93. PMID: 17168665
  3. The multiple faces of quercetin in neuroprotection.  |  Ossola, B., et al. 2009. Expert Opin Drug Saf. 8: 397-409. PMID: 19538101
  4. In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity.  |  Tiong, KH., et al. 2010. Xenobiotica. 40: 458-66. PMID: 20402563
  5. Quercetin as a systemic chemopreventative agent: structural and functional mechanisms.  |  Mendoza, EE. and Burd, R. 2011. Mini Rev Med Chem. 11: 1216-21. PMID: 22070678
  6. Quercetin inhibits invasion and angiogenesis of esophageal cancer cells.  |  Liu, Y., et al. 2021. Pathol Res Pract. 222: 153455. PMID: 33962176
  7. The role of quercetin in plants.  |  Singh, P., et al. 2021. Plant Physiol Biochem. 166: 10-19. PMID: 34087741
  8. A review on pharmacological activities and synergistic effect of quercetin with small molecule agents.  |  Zou, H., et al. 2021. Phytomedicine. 92: 153736. PMID: 34560520
  9. Anti-fatigue effect of quercetin on enhancing muscle function and antioxidant capacity.  |  Chen, X., et al. 2021. J Food Biochem. 45: e13968. PMID: 34651301
  10. Quercetin Inhibits Glioblastoma Growth and Prolongs Survival Rate through Inhibiting Glycolytic Metabolism.  |  Wang, L., et al. 2022. Chemotherapy. 67: 132-141. PMID: 35249013
  11. Antimicrobial Activity of Quercetin: An Approach to Its Mechanistic Principle.  |  Nguyen, TLA. and Bhattacharya, D. 2022. Molecules. 27: PMID: 35458691
  12. Quercetin binding accelerates prion fibrillation into proteinase sensitive and loosely structured amyloids.  |  Yu, KH., et al. 2022. Biomed Pharmacother. 151: 113177. PMID: 35676783
  13. Anti-Allergic Effects of Quercetin and Quercetin Liposomes in RBL-2H3 Cells.  |  Zhang, Y., et al. 2022. Endocr Metab Immune Disord Drug Targets.. PMID: 35761488

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Quercetin, 100 mg

sc-206089
100 mg
$11.00

Quercetin, 500 mg

sc-206089A
500 mg
$17.00

Quercetin, 25 g

sc-206089B
25 g
$49.00

Quercetin, 100 g

sc-206089E
100 g
$108.00

Quercetin, 250 g

sc-206089C
250 g
$245.00

Quercetin, 1 kg

sc-206089D
1 kg
$918.00

Preciso fazer um verniz de quercetina em uma concentração de 5%, quanto em gramas preciso para preparar o materialW

Asked by: pat27
5% pode ser % em peso ou % molar.
Answered by: Technical Service
Date published: 2024-04-18

qual a densidade, área de superfície e diâmetro das partículas de quercetina

Asked by: pat27
Thank you for your question. This compound has a density of 1.80 g/cm3. Surface area and particle size are not determined.
Answered by: Tech Support Europe
Date published: 2023-04-12

I need to prepare a solution of ethanol (2000ml) of quercetin 117395 concentration 0.01M. what is the mass of quercetin i need to have? and what is the density of quercetin? Thank you.

Asked by: Lux15
Thank you for your question. Our Quercetin product is a solid so there is no density. In order use 2000 ml of ethanol to make 0.01M solution, you would need to add 6.04 g of sc-212920 to get 0.01M.
Answered by: Technical Support
Date published: 2017-01-19

Is this product synthetic?

Asked by: hawkeye11
Thank you for your question. Quercetin, sc-206089, is of plant origin.
Answered by: TechService7
Date published: 2016-12-23
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Rated 4 out of 5 by from Purchased materialWe bought this material and it worked out great for us.
Date published: 2020-09-05
Rated 5 out of 5 by from Tiong et alTiong et al. (PubMed ID 20402563) found that quercetin competitively inhibited Coumarin 7-hydroxylase activity via cytochrome P450 2A6 (CYP2A6). -SCBT Publication Review
Date published: 2015-05-01
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Quercetin is rated 4.5 out of 5 by 2.
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