Date published: 2025-12-18

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Pyrocatechol (CAS 120-80-9)

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Alternate Names:
1,2-Benzenediol; 1,2-Dihydroxybenzene; Catechol
Application:
Pyrocatechol is a useful precursor to various pesticides, flavors, and fragrances
CAS Number:
120-80-9
Molecular Weight:
110.11
Molecular Formula:
C6H6O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pyrocatechol, also known as 1,2-dihydroxybenzene is an organic compound. This white, crystalline solid demonstrates solubility in water, alcohol, and ether. In scientific research, pyrocatechol serves as a fundamental component in a multitude of applications. In vitro, pyrocatechol plays a role in investigating the mechanisms of action of enzymes and other proteins. Notably, pyrocatechol functions as a competitive inhibitor of the enzyme catechol-O-methyltransferase (COMT). This enzyme is responsible for metabolizing catecholamines such as dopamine, epinephrine, and norepinephrine..


Pyrocatechol (CAS 120-80-9) References

  1. Pyrocatechol violet as a detection reagent for cations.  |  MACEK, K. and MORAVEK, L. 1956. Nature. 178: 102-3. PMID: 13348643
  2. Pyrocatechol violet as a marker to characterize liposomal membrane permeability using the chelation and the first-order derivative spectrophotometry.  |  Jin, Y., et al. 2005. J Pharm Biomed Anal. 37: 379-82. PMID: 15708681
  3. Kinetics of deposition and stability of pyrocatechol -FeIII coordinated films.  |  Meyer, C., et al. 2017. Mater Sci Eng C Mater Biol Appl. 72: 620-624. PMID: 28024630
  4. Contrasting roles of phenol and pyrocatechol on the degradation of 4-chlorophenol in a photocatalytic-biological reactor.  |  Zhang, C., et al. 2017. Environ Sci Pollut Res Int. 24: 24725-24731. PMID: 28942472
  5. Cobalt-Catalyzed C-H Acetoxylation of Phenols with Removable Monodentate Directing Groups: Access to Pyrocatechol Derivatives.  |  Gou, Q., et al. 2020. Org Lett. 22: 1966-1971. PMID: 32073867
  6. Pyrocatechol violet impregnated magnetic graphene oxide for magnetic solid phase microextraction of copper in water, black tea and diet supplements.  |  Ozkantar, N., et al. 2020. Food Chem. 321: 126737. PMID: 32278275
  7. Molecular modeling and in vitro study on pyrocatechol as potential pharmacophore of CD151 inhibitor.  |  Akella, M. and Malla, R. 2020. J Mol Graph Model. 100: 107681. PMID: 32738620
  8. Pyrocatechol contact allergy from a permanent cream dye for eyelashes and eyebrows.  |  Andersen, KE. and Carlsen, L. 1988. Contact Dermatitis. 18: 306-7. PMID: 3416595
  9. Detection of glyphosate with a copper(II)-pyrocatechol violet based GlyPKit.  |  Yadav, P. and Zelder, F. 2021. Anal Methods. 13: 4354-4360. PMID: 34570143
  10. Simultaneous TLC-densitometric analysis of catechin, pyrocatechol and quercetine in gambir block from Pesisir Selatan.  |  Kamal, S., et al. 2022. Heliyon. 8: e08985. PMID: 35252606
  11. A novel dual-channel fluorescence sensor array based on the reaction of o-phenylenediamine/3,4-diaminotoluene and pyrocatechol for Baijiu discrimination.  |  Wu, M., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 278: 121273. PMID: 35537257
  12. Selected organic dyes (carminic acid, pyrocatechol violet and dithizone) sensitized metal (silver, neodymium) doped TiO2/ZnO nanostructured materials: A photoanode for hybrid bulk heterojunction solar cells.  |  Ullah, N., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 278: 121387. PMID: 35597162
  13. Pyrocatechol Alleviates Cisplatin-Induced Acute Kidney Injury by Inhibiting ROS Production.  |  Xie, X., et al. 2022. Oxid Med Cell Longev. 2022: 2158644. PMID: 36193072

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pyrocatechol, 100 g

sc-215763
100 g
$43.00

Pyrocatechol, 500 g

sc-215763A
500 g
$158.00