Date published: 2025-10-16

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Pyridoxamine-5′-phosphate (CAS 529-96-4)

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CAS Number:
529-96-4
Purity:
≥98%
Molecular Weight:
248.17
Molecular Formula:
C8H13N2O5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pyridoxamine-5′-phosphate (PMP) is a naturally occurring metabolite of vitamin B6 that is found in a variety of foods, including grains, legumes, and vegetables. It plays a role in the regulation of glucose and lipid metabolism. It also has antioxidant, anti-inflammatory, and anti-cancer properties. This makes Pyridoxamine-5′-phosphate beneficial for scientific research related to a variety of conditions, including cardiovascular disease, diabetes, cancer, and neurodegenerative diseases.


Pyridoxamine-5′-phosphate (CAS 529-96-4) References

  1. Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase.  |  di Salvo, ML., et al. 2002. J Mol Biol. 315: 385-97. PMID: 11786019
  2. Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana.  |  Sang, Y., et al. 2007. FEBS Lett. 581: 344-8. PMID: 17224143
  3. Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases.  |  Seo, JH., et al. 2011. Biotechnol Bioeng. 108: 253-63. PMID: 20824676
  4. Crystal structure of glutamate-1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate.  |  Ge, H., et al. 2010. Biochem Biophys Res Commun. 402: 356-60. PMID: 20946885
  5. Complexes of vitamin B6XX: equilibrium and mechanistic studies of the reaction of pyridoxal-5'-phosphate with pyridoxamine-5'-phosphate in the presence of copper(II).  |  Marafie, HM., et al. 1989. J Inorg Biochem. 37: 7-16. PMID: 2795002
  6. Activation of glutamate apodecarboxylase by succinic semialdehyde and pyridoxamine 5'-phosphate.  |  Porter, TG., et al. 1986. J Neurochem. 47: 468-71. PMID: 2874189
  7. The stereospecific labilization of the C-4' pro-S hydrogen of pyridoxamine 5'-phosphate is abolished in (Lys258----Ala) aspartate aminotransferase.  |  Kochhar, S., et al. 1987. J Biol Chem. 262: 11446-8. PMID: 3114245
  8. Stereospecific labilization of the C-4' pro-S hydrogen of pyridoxamine 5'-phosphate in aspartate aminotransferase.  |  Tobler, HP., et al. 1986. J Biol Chem. 261: 7105-8. PMID: 3711077
  9. Interaction between pyridoxamine 5'-phosphate and apo-aspartate aminotransferase from pig heart. Evidence for a negative cooperativity.  |  Arrio-Dupont, M. 1972. Eur J Biochem. 30: 307-17. PMID: 4676995
  10. The rotational mobility of pyridoxamine 5-phosphate.  |  Churchich, JE. 1970. J Biol Chem. 245: 448-9. PMID: 5412067
  11. The interaction of pyridoxamine 5-phosphate with aspartate aminotransferase.  |  Churchich, JE. and Farrelly, JG. 1969. J Biol Chem. 244: 72-6. PMID: 5773291
  12. Mechanism of binding of pyridoxamine 5-phosphate to the apoenzyme aspartate aminotransferase. Fluorescence studies.  |  Churchich, JE. and Farrelly, JG. 1969. J Biol Chem. 244: 3685-90. PMID: 5794234
  13. Effect of different levels of vitamin B6 in the diet of rats on the content of pyridoxamine-5'-phosphate and pyridoxal-5'-phosphate in the liver.  |  van den Berg, H., et al. 1982. Int J Vitam Nutr Res. 52: 407-16. PMID: 7160968

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pyridoxamine-5′-phosphate, 10 mg

sc-236522
10 mg
$764.00