Date published: 2026-5-3

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Pyrene (CAS 129-00-0)

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Alternate Names:
Benzo[def]phenanthrene
CAS Number:
129-00-0
Molecular Weight:
202.26
Molecular Formula:
C16H10
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pyrene, a polycyclic aromatic hydrocarbon (PAH), plays a vital role in scientific research due to its widespread use. As a white, crystalline solid with a high melting point and low vapor pressure, it finds application in various synthetic materials like polymers, plastics, and coatings. Beyond that, Pyrene serves as a valuable tracer in the investigation of environmental pollutants. In scientific studies, Pyrene′s versatility is evident. It has been extensively employed in shedding light on the metabolism of carbohydrates, lipids, and proteins. Moreover, it has been instrumental in delving into cellular signaling pathways, notably the regulation of gene expression. When examining the intricacies of proteins and nucleic acids, Pyrene has proven itself as an invaluable fluorescent label, aiding researchers in their endeavors. Being a lipophilic molecule, Pyrene effortlessly interacts with a multitude of biological molecules like proteins, lipids, and nucleic acids. Though the exact mechanism of its action remains not entirely understood, it is believed to target specific sites on proteins and nucleic acids, inducing notable changes in their structure and function. This aspect opens up exciting possibilities for further research and applications in the scientific realm.


Pyrene (CAS 129-00-0) References

  1. Pyrene: a probe to study protein conformation and conformational changes.  |  Bains, G., et al. 2011. Molecules. 16: 7909-35. PMID: 22143550
  2. Pyrene chromophores for the photoreversal of psoralen interstrand crosslinks.  |  Stadler, JM. and Stafforst, T. 2014. Org Biomol Chem. 12: 5260-6. PMID: 24922335
  3. Pyrene functionalized molecular beacon with pH-sensitive i-motif in a loop.  |  Dembska, A. and Juskowiak, B. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 150: 928-33. PMID: 26123509
  4. A pyrene-bridged macrocage showing no excimer fluorescence.  |  Shionari, H., et al. 2015. Org Biomol Chem. 13: 10511-6. PMID: 26336857
  5. Pyrene biodegradation enhancement potential of lipopeptide biosurfactant produced by Paenibacillus dendritiformis CN5 strain.  |  Bezza, FA. and Chirwa, EMN. 2017. J Hazard Mater. 321: 218-227. PMID: 27627697
  6. Biodegradation of pyrene by Candida sp. S1 under high salinity conditions.  |  Hadibarata, T., et al. 2017. Bioprocess Biosyst Eng. 40: 1411-1418. PMID: 28612166
  7. Pyrene-Based Blue AIEgen: Enhanced Hole Mobility and Good EL Performance in Solution-Processed OLEDs.  |  Yang, J., et al. 2017. Molecules. 22: PMID: 29207563
  8. Pyrene metabolites by bacterium enhancing cell division of green alga Selenastrum capricornutum.  |  Li, X., et al. 2019. Sci Total Environ. 689: 287-294. PMID: 31276996
  9. Do pyrene and Kandelia obovata improve removal of BDE-209 in mangrove soils?  |  Li, R., et al. 2020. Chemosphere. 240: 124873. PMID: 31574439
  10. Unusual Fluorescence Behavior of Pyrene-Amine Containing Dendrimers.  |  Ruiu, A., et al. 2019. Molecules. 24: PMID: 31726647
  11. Effect of pyrene on formation of natural silver nanoparticles via reduction of silver ions by humic acid under UV irradiation.  |  Liu, M., et al. 2020. Chemosphere. 247: 125937. PMID: 31978665
  12. Pyrene Excimer Formation (PEF) and Its Application to the Study of Polypeptide Dynamics.  |  Casier, R. and Duhamel, J. 2022. Langmuir. 38: 3623-3629. PMID: 35291766
  13. A novel pyrene-based fluorescent probe for Al3+ detection.  |  Liu, Y., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 287: 122085. PMID: 36379088

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pyrene, 25 g

sc-485195
25 g
$47.00