Pyrantel Pamoate (CAS 22204-24-6)
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Pyrantel Pamoate is utilized in veterinary research in the study of helminthic infections. It acts by selectively targeting nicotinic acetylcholine receptors in the muscle cells of nematodes. The research includes evaluating the effects of Pyrantel Pamoate on various parasitic worms, with a focus on dose-response relationships and the spectrum of activity. Investigations also delve into the mechanisms that contribute to resistance, which are of significant concern in maintaining the long-term utility of anthelmintics. Additionally, Pyrantel Pamoate is employed in ecological studies to understand the environmental impact of anthelmintic use, particularly its effects on non-target organisms and the potential for environmental persistence.
Pyrantel Pamoate (CAS 22204-24-6) References
- Common intestinal parasites. | Kucik, CJ., et al. 2004. Am Fam Physician. 69: 1161-8. PMID: 15023017
- Efficacy of ivermectin and pyrantel pamoate combined in a chewable formulation against heartworm, hookworm, and ascarid infections in dogs. | Clark, JN., et al. 1992. Am J Vet Res. 53: 517-20. PMID: 1586021
- Pyrantel pamoate resistance in horses receiving daily administration of pyrantel tartrate. | Brazik, EL., et al. 2006. J Am Vet Med Assoc. 228: 101-3. PMID: 16426178
- Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. | Reinemeyer, CR., et al. 2006. Vet Parasitol. 138: 234-9. PMID: 16530970
- Simultaneous determination of mebendazole and pyrantel pamoate from tablets by high performance liquid chromatography-reverse phase (RP-HPLC). | Argekar, AP., et al. 1997. Talanta. 44: 1959-65. PMID: 18966940
- Efficacy of pyrantel pamoate and ivermectin paste formulations against naturally acquired Oxyuris equi infections in horses. | Reinemeyer, CR., et al. 2010. Vet Parasitol. 171: 106-10. PMID: 20307935
- Efficacy of pyrantel pamoate against a macrocyclic lactone-resistant isolate of Parascaris equorum in horses. | Reinemeyer, CR., et al. 2010. Vet Parasitol. 171: 111-5. PMID: 20307936
- The efficacy of pyrantel pamoate against ascarids and hookworms in cats. | Ridley, RK., et al. 1991. Vet Res Commun. 15: 37-44. PMID: 2048286
- Pharmacokinetics of praziquantel and pyrantel pamoate combination following oral administration in cats. | Arion, A., et al. 2018. J Feline Med Surg. 20: 900-904. PMID: 29017390
- Reduced Efficacy of Fenbendazole and Pyrantel Pamoate Treatments against Intestinal Nematodes of Stud and Performance Horses. | Zanet, S., et al. 2021. Vet Sci. 8: PMID: 33807857
- In vivo efficacy of pyrantel pamoate as a post-exposure prophylactic for rat lungworm (Angiostrongylus cantonensis). | Jacob, J., et al. 2022. Int J Parasitol Drugs Drug Resist. 19: 1-5. PMID: 35436745
- Investigation of the Efficacy of Pyrantel Pamoate, Mebendazole, Albendazole, and Ivermectin against Baylisascaris schroederi in Captive Giant Pandas. | Lu, Y., et al. 2022. Animals (Basel). 13: PMID: 36611749
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pyrantel Pamoate, 5 g | sc-205823 | 5 g | $84.00 | |||
Pyrantel Pamoate, 10 g | sc-205823A | 10 g | $136.00 |