Molecular structure of Putrescine dihydrochloride, CAS Number: 333-93-7
Putrescine dihydrochloride (CAS 333-93-7)
See product citations (2)
Alternate Names:
1,4-Diaminobutane • 2HCl; Tetramethylenediamine • 2HCl
Application:
Putrescine dihydrochloride is an NMDA agonist
CAS Number:
333-93-7
Purity:
≥98%
Molecular Weight:
161.08
Molecular Formula:
C4H12N2•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Putrescine dihydrochloride can bind to the polyamine modulatory site of the NMDA (N-methyl D-aspartate) receptor and potentiate NMDA-induced currents. Polyamines belong to a group of aliphatic amines that are selective and act on different ion channels. Putrescine dihydrocloride is a precursor of spermidine. Putrescine dihydrochloride is an activator of NMDA.
Putrescine dihydrochloride (CAS 333-93-7) References
- Polyamines potentiate NMDA induced whole-cell currents in cultured striatal neurons. | Sprosen, TS. and Woodruff, GN. 1990. Eur J Pharmacol. 179: 477-8. PMID: 1694770
- Metabolic engineering of Escherichia coli for the production of putrescine: a four carbon diamine. | Qian, ZG., et al. 2009. Biotechnol Bioeng. 104: 651-62. PMID: 19714672
- Putrescine production by engineered Corynebacterium glutamicum. | Schneider, J. and Wendisch, VF. 2010. Appl Microbiol Biotechnol. 88: 859-68. PMID: 20661733
- Changes in urocanic acid, histamine, putrescine and cadaverine levels in Indian mackerel (Rastrelliger kanagurta) during storage at different temperatures. | Zare, D., et al. 2013. Food Chem. 139: 320-5. PMID: 23561112
- Peri-ovulatory putrescine supplementation reduces embryo resorption in older mice. | Tao, Y., et al. 2015. Hum Reprod. 30: 1867-75. PMID: 26082481
- Putrescine supplementation during in vitro maturation of aged mouse oocytes improves the quality of blastocysts. | Liu, D., et al. 2017. Reprod Fertil Dev. 29: 1392-1400. PMID: 27319359
- Ornithine Decarboxylase-Mediated Production of Putrescine Influences Ganoderic Acid Biosynthesis by Regulating Reactive Oxygen Species in Ganoderma lucidum. | Wu, CG., et al. 2017. Appl Environ Microbiol. 83: PMID: 28802268
- Biological conversion of methane to putrescine using genome-scale model-guided metabolic engineering of a methanotrophic bacterium Methylomicrobium alcaliphilum 20Z. | Nguyen, LT. and Lee, EY. 2019. Biotechnol Biofuels. 12: 147. PMID: 31223337
- Putrescine mitigates intestinal atrophy through suppressing inflammatory response in weanling piglets. | Liu, B., et al. 2019. J Anim Sci Biotechnol. 10: 69. PMID: 31516701
- Putrescine and Its Metabolic Precursor Arginine Promote Biofilm and c-di-GMP Synthesis in Pseudomonas aeruginosa. | Liu, Z., et al. 2022. J Bacteriol. 204: e0029721. PMID: 34723645
- Electrostatic control of enzyme reactions: the mechanism of inhibition of glucose oxidase by putrescine. | Voet, JG. and Andersen, EC. 1984. Arch Biochem Biophys. 233: 88-92. PMID: 6465905
- Labeled putrescine as a probe in brain tumors. | Volkow, N., et al. 1983. Science. 221: 673-5. PMID: 6603020
- Interactions of polyamines with neuronal ion channels. | Scott, RH., et al. 1993. Trends Neurosci. 16: 153-60. PMID: 7682349
Activator of:
NMDA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Putrescine dihydrochloride, 5 mg | sc-202786E | 5 mg | $23.00 | |||
Putrescine dihydrochloride, 5 mg | sc-202786E-CW | 5 mg | $27.00 | |||
Putrescine dihydrochloride, 25 g | sc-202786 | 25 g | $32.00 | |||
Putrescine dihydrochloride, 100 g | sc-202786A | 100 g | $84.00 | |||
Putrescine dihydrochloride, 250 g | sc-202786B | 250 g | $146.00 | |||
Putrescine dihydrochloride, 1 kg | sc-202786C | 1 kg | $490.00 | |||
Putrescine dihydrochloride, 5 kg | sc-202786D | 5 kg | $2393.00 |