Molecular structure of Purpurin, CAS Number: 81-54-9
Purpurin (CAS 81-54-9)
Alternate Names:
1,2,4-Trihydroxy-9,10-anthracenedione
Application:
Purpurin is a xanthine oxidase inhibitor
CAS Number:
81-54-9
Molecular Weight:
256.21
Molecular Formula:
C14H8O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Purpurin is a xanthine oxidase inhibitor that inhibits azoxymethane-induced aberrant crypt foci.
Purpurin (CAS 81-54-9) References
- Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer's disease-like symptoms in animal model. | Viswanathan, GK., et al. 2020. Cell Mol Life Sci. 77: 2795-2813. PMID: 31562564
- Purpurin: A natural anthraquinone with multifaceted pharmacological activities. | Singh, J., et al. 2021. Phytother Res. 35: 2418-2428. PMID: 33254282
- Purpurin binding interacts with LHPP protein that inhibits PI3K/AKT phosphorylation and induces apoptosis in colon cancer cells HCT-116. | Li, Z., et al. 2021. J Biochem Mol Toxicol. 35: e22665. PMID: 33368780
- Purpurin, a anthraquinone induces ROS-mediated A549 lung cancer cell apoptosis via inhibition of PI3K/AKT and proliferation. | Bo, S., et al. 2021. J Pharm Pharmacol. 73: 1101-1108. PMID: 33877317
- Neuroprotective Effects of Purpurin Against Ischemic Damage via MAPKs, Bax, and Oxidative Stress Cascades in the Gerbil Hippocampus. | Kim, W., et al. 2022. Mol Neurobiol. 59: 2580-2592. PMID: 35094304
- Copper-mediated DNA damage caused by purpurin, a natural anthraquinone. | Kobayashi, H., et al. 2022. Genes Environ. 44: 15. PMID: 35527257
- Purpurin suppresses atopic dermatitis via TNF-α/IFN-γ-induced inflammation in HaCaT cells. | Oh, JH., et al. 2022. Int J Immunopathol Pharmacol. 36: 3946320221111135. PMID: 35794850
- Protective activity of purpurin against d-galactosamine and lipopolysaccharide-induced hepatorenal injury by upregulation of heme oxygenase-1 in the RBC degradation cycle. | Rakshit, S., et al. 2022. J Biochem Mol Toxicol. 36: e23168. PMID: 35838105
- Purpurin ameliorates alcohol-induced hepatotoxicity by reducing ROS generation and promoting Nrf2 expression. | Hussain, Y., et al. 2022. Life Sci. 309: 120964. PMID: 36115584
- The Effective Treatment of Purpurin on Inflammation and Adjuvant-Induced Arthritis. | Zeng, W., et al. 2023. Molecules. 28: PMID: 36615560
- Purpurin ameliorates D-galactose-induced aging phenotypes in mouse hippocampus by reducing inflammatory responses. | Kwon, HJ., et al. 2023. Neurochem Int. 167: 105552. PMID: 37230197
- Aberrant crypts as a biomarker for colon cancer: evaluation of potential chemopreventive agents in the rat. | Wargovich, MJ., et al. 1996. Cancer Epidemiol Biomarkers Prev. 5: 355-60. PMID: 9162301
- Inhibition of xanthine oxidase by hydroxylated anthraquinones and related compounds. | Sheu, SY. and Chiang, HC. 1997. Anticancer Res. 17: 3293-7. PMID: 9413162
Inhibitor of:
Xanthine Oxidase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Purpurin, 5 g | sc-205822 | 5 g | $46.00 | |||
Purpurin, 25 g | sc-205822A | 25 g | $161.00 | |||
Purpurin, 100 g | sc-205822B | 100 g | $398.00 | |||
Purpurin, 250 g | sc-205822C | 250 g | $867.00 |