Molecular structure of Punicalagin, CAS Number: 65995-63-3
Punicalagin (CAS 65995-63-3)
See product citations (4)
Alternate Names:
Punicalagin is also known as a pomegranate ellagitannin.
Application:
Punicalagin is an ellagitannin reported to produce antioxidant, anti-inflammatory, and anticancer effects.
CAS Number:
65995-63-3
Purity:
≥40%
Molecular Weight:
1084.72
Molecular Formula:
C48H28O30
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Punicalagin is a major ellagitannin. Reports have been made of Punicalagin being antioxidant and anti-inflammatory. Its ability to scavenge free radicals and chelate metal ions protects cells and biomolecules from oxidative damage. This chelation capacity plays a role in reducing the catalytic potential of metals that can induce oxidative damage and contributes to the stabilization of the molecule itself, enhancing its antioxidant effects. Myocardial damage can also be controlled by Punicalagin, via AMPK-mediated modulation of mitochondria and phase II enzymes.
Punicalagin (CAS 65995-63-3) References
- Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway. | Cao, Y., et al. 2019. Nutrients. 11: PMID: 31731808
- Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway. | An, X., et al. 2020. Nutrients. 12: PMID: 32456088
- Punicalagin Damages the Membrane of Salmonella Typhimurium. | Li, G., et al. 2020. J Food Prot. 83: 2102-2106. PMID: 32663262
- Punicalagin is a neuraminidase inhibitor of influenza viruses. | Li, P., et al. 2021. J Med Virol. 93: 3465-3472. PMID: 32827314
- Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway. | Ge, G., et al. 2022. Sci China Life Sci. 65: 588-603. PMID: 34125371
- Punicalagin attenuates osteoarthritis progression via regulating Foxo1/Prg4/HIF3α axis. | Liu, F., et al. 2021. Bone. 152: 116070. PMID: 34171516
- Physiological and Immune Functions of Punicalagin. | Venusova, E., et al. 2021. Nutrients. 13: PMID: 34201484
- Punicalagin in Cancer Prevention-Via Signaling Pathways Targeting. | Berdowska, I., et al. 2021. Nutrients. 13: PMID: 34444893
- Punicalagin alleviates renal injury via the gut-kidney axis in high-fat diet-induced diabetic mice. | Hua, Q., et al. 2022. Food Funct. 13: 867-879. PMID: 34989745
- Punicalagin Regulates Signaling Pathways in Inflammation-Associated Chronic Diseases. | Xu, J., et al. 2021. Antioxidants (Basel). 11: PMID: 35052533
- Punicalagin Attenuates Neuronal Apoptosis by Upregulating 5-Hydroxymethylcytosine in the Diabetic Mouse Brain. | He, X., et al. 2022. J Agric Food Chem. 70: 4995-5004. PMID: 35412829
- Punicalagin-Loaded Alginate/Chitosan-Gallol Hydrogels for Efficient Wound Repair and Hemostasis. | Ju, J., et al. 2022. Polymers (Basel). 14: PMID: 36015503
- Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways. | Yu, L. and Li, J. 2022. Acta Pharm. 72: 561-573. PMID: 36651367
Inhibitor of:
SLC22A12.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Punicalagin, 1 g | sc-484442 | 1 g | $200.00 | |||
Punicalagin, 5 g | sc-484442A | 5 g | $626.00 |