
PU.1 Antibody (B-9) is a mouse monoclonal IgG1 antibody that detects PU.1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PU.1 is a critical transcription factor belonging to the Ets family, playing a vital role in the regulation of gene expression during lymphoid development and immune response. PU.1 is primarily located in the nucleus, where PU.1 binds to specific DNA sequences to activate or repress target genes essential for B cell differentiation and function. PU.1′s nuclear localization enables interaction with other transcription factors and co-regulators, facilitating the transcriptional programs necessary for hematopoiesis and immune cell maturation. PU.1 is expressed in a diverse range of hematopoietic cells, including B cells, early T-cells, and myeloid cells, underscoring PU.1′s pivotal role in the immune system. Anti-PU.1 antibody (B-9) serves as an invaluable tool for researchers studying the mechanisms of immune cell development and function, as well as the underlying pathways involved in various hematological disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PU.1/Spi1 Antibody (B-9) | sc-390659 | 200 µg/ml | $322.00 | |||
PU.1/Spi1 Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-540830 | 200 µg Ab; 10 µg BP | $361.00 | |||
PU.1/Spi1 Antibody (B-9): m-IgG1 BP-HRP Bundle | sc-542399 | 200 µg Ab; 20 µg BP | $361.00 | |||
PU.1/Spi1 (B-9) Neutralizing Peptide | sc-390659 P | 100 µg/0.5 ml | $69.00 | |||
PU.1/Spi1 Antibody (B-9) X | sc-390659 X | 200 µg/0.1 ml | $322.00 |