Date published: 2026-5-5

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Pteroic acid (CAS 119-24-4)

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CAS Number:
119-24-4
Purity:
≥92%
Molecular Weight:
312.28
Molecular Formula:
C14H12N6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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As a component of coenzyme A, it aids in regulating enzyme activity and energy production. Moreover, pteroic acid serves as a precursor to significant compounds like folic acid and vitamin B12. It facilitates the examination of how different compounds influence cell growth and development. Derived from coenzyme A (CoA), pteroic acid acts as a cofactor in several metabolic pathways.


Pteroic acid (CAS 119-24-4) References

  1. In vitro selection of RNA molecules that inhibit the activity of ricin A-chain.  |  Hesselberth, JR., et al. 2000. J Biol Chem. 275: 4937-42. PMID: 10671531
  2. Application of halogeno-ketones to the synthesis of pteridines, including pteroic acid.  |  KING, FE. and SPENSLEY, PC. 1949. Nature. 164: 574. PMID: 18142455
  3. 7-Substituted pterins provide a new direction for ricin A chain inhibitors.  |  Pruet, JM., et al. 2011. Eur J Med Chem. 46: 3608-15. PMID: 21641093
  4. Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents.  |  Zhao, Y., et al. 2016. Bioorg Med Chem Lett. 26: 3950-4. PMID: 27423480
  5. Activation of excitatory amino acid receptors may mediate the folate-induced stimulation of locomotor activity after bilateral injection into the rat nucleus accumbens.  |  Stephens, RL., et al. 1986. J Pharmacol Exp Ther. 239: 627-33. PMID: 3025414
  6. A spectrophotometric method for determining the amount of folic acid in fortified salt.  |  Modupe, O., et al. 2020. J Agric Food Res. 2: 100060. PMID: 33458702
  7. Deciphering the competitive inhibition of dihydropteroate synthase by 8 marcaptoguanine analogs: enhanced potency in phenylsulfonyl fragments.  |  Das, BK. and Chakraborty, D. 2022. J Biomol Struct Dyn. 40: 13083-13102. PMID: 34581241
  8. Synthesis, Characterization and Photocleavage of Bis-decyl Pteroic Acid: A Folate Derivative with Affinity to Biomembranes†.  |  Fonseca, JL., et al. 2023. Photochem Photobiol. 99: 593-604. PMID: 36478217
  9. Activation of folypolyglutamate synthetase by pteroic acid.  |  Vickers, PJ., et al. 1985. Can J Biochem Cell Biol. 63: 777-9. PMID: 3840051
  10. Abnormal folate metabolism in feed-related anemia of cultured channel catfish.  |  Butterworth, CE., et al. 1986. Proc Soc Exp Biol Med. 181: 49-58. PMID: 3945624
  11. Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R: partial purification and properties of methionyl-transfer ribonucleic acid synthetase and methionyl-transfer ribonucleic acid formyltransferase.  |  Samuel, CE. and Rabinowitz, JC. 1974. J Bacteriol. 118: 21-31. PMID: 4206871
  12. Characterization of the function of mammalian folylpolyglutamate synthetase (FPGS).  |  Moran, RG. 1983. Adv Exp Med Biol. 163: 327-39. PMID: 6577780
  13. Structural analysis of ricin and implications for inhibitor design.  |  Robertus, JD., et al. 1996. Toxicon. 34: 1325-34. PMID: 9027989
  14. Structure-based identification of a ricin inhibitor.  |  Yan, X., et al. 1997. J Mol Biol. 266: 1043-9. PMID: 9086280
  15. High performance liquid chromatographic determination of folic acid and its photodegradation products in the presence of riboflavin.  |  Akhtar, MJ., et al. 1997. J Pharm Biomed Anal. 16: 95-9. PMID: 9447556

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pteroic acid, 25 mg

sc-250800
25 mg
$62.00

Pteroic acid, 50 mg

sc-250800A
50 mg
$109.00