Date published: 2025-9-18

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PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt)

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Alternate Names:
DOPI-3,4-P2; Phosphatidylinositol-3,4-bisphosphate C-8
Application:
PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) is a phospholipid that plays a role in cell signalling
Molecular Weight:
812.5
Molecular Formula:
C25H46O19P33Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) is a synthetic derivative of phosphatidylinositol (PtdIns), a vital phospholipid involved in various cellular processes. This chemical has emerged as a powerful tool in scientific research for investigating the signaling pathways mediated by phosphoinositides. Specifically, PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) has been utilized to explain the roles of phosphoinositides in cellular signaling cascades, particularly those related to cell growth, proliferation, and cytoskeletal dynamics. By modulating the levels and distribution of phosphoinositides within cells, researchers can probe the specific functions of PtdIns-(3,4)-P2 in regulating downstream effectors, such as protein kinases and ion channels. Moreover, studies employing this chemical have provided insights into the mechanisms underlying phosphoinositide-mediated signaling events, including receptor tyrosine kinase activation, phosphoinositide 3-kinase (PI3K) signaling, and cytoskeletal remodeling. Additionally, PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) has been instrumental in deciphering the cross-talk between phosphoinositide signaling pathways and other cellular processes, contributing to a better understanding of cell biology and potential targets for various diseases. Through its precise manipulation of phosphoinositide signaling, this chemical facilitates the exploration of novel research avenues aimed at unraveling the complexities of cellular signaling networks.


PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) References

  1. Inositol phosphate biochemistry.  |  Majerus, PW. 1992. Annu Rev Biochem. 61: 225-50. PMID: 1323235
  2. Polyphosphoinositides produced by phosphatidylinositol 3-kinase are poor substrates for phospholipases C from rat liver and bovine brain.  |  Serunian, LA., et al. 1989. J Biol Chem. 264: 17809-15. PMID: 2553693
  3. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins.  |  Exton, JH. 1996. Annu Rev Pharmacol Toxicol. 36: 481-509. PMID: 8725399

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt), 100 µg

sc-224236
100 µg
$56.00

PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt), 500 µg

sc-224236A
500 µg
$373.00