Date published: 2026-2-12

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PtdIns-(1,2-dioctanoyl) (sodium salt)

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Alternate Names:
Phosphatidylinositol C-8; DOPI
Molecular Weight:
608.6
Molecular Formula:
C25H46O13P•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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PtdIns-(1,2-dioctanoyl) (sodium salt) is a synthetic derivative of phosphatidylinositol (PtdIns), a crucial phospholipid component of cellular membranes. This chemical variant has gained prominence as a research tool for elucidating the roles and signaling mechanisms mediated by phosphoinositides in various cellular processes. Specifically, PtdIns-(1,2-dioctanoyl) (sodium salt) has been utilized to investigate the functions of phosphoinositides in intracellular membrane trafficking, signaling transduction, and cytoskeletal organization. As a mimic of natural phosphatidylinositols, it enables researchers to manipulate the levels and distribution of phosphoinositides within cells, facilitating the dissection of their specific roles in cellular physiology. Additionally, studies employing PtdIns-(1,2-dioctanoyl) (sodium salt) have shed light on the regulatory mechanisms governing phosphoinositide metabolism, including their synthesis, turnover, and spatial organization within cellular membranes. Furthermore, this chemical tool has been instrumental in elucidating the crosstalk between phosphoinositide signaling and other cellular pathways, such as protein kinase cascades and ion channel regulation. Overall, the use of PtdIns-(1,2-dioctanoyl) (sodium salt) in research provides valuable insights into the complex interplay between phosphoinositides and cellular processes, paving the way for a deeper understanding of cell biology and potential targets for various diseases.


PtdIns-(1,2-dioctanoyl) (sodium salt) References

  1. Inositol phosphate biochemistry.  |  Majerus, PW. 1992. Annu Rev Biochem. 61: 225-50. PMID: 1323235
  2. Evaluation of phosphatidylinositol-4-kinase IIIα as a hepatitis C virus drug target.  |  Vaillancourt, FH., et al. 2012. J Virol. 86: 11595-607. PMID: 22896614
  3. Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in Drosophila wing development.  |  Zhang, J., et al. 2023. Sci Signal. 16: eadd6834. PMID: 37847757
  4. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins.  |  Exton, JH. 1996. Annu Rev Pharmacol Toxicol. 36: 481-509. PMID: 8725399

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PtdIns-(1,2-dioctanoyl) (sodium salt), 100 µg

sc-224233
100 µg
$96.00

PtdIns-(1,2-dioctanoyl) (sodium salt), 500 µg

sc-224233A
500 µg
$435.00