Molecular structure of PTACH, CAS Number: 848354-66-5
PTACH (CAS 848354-66-5)
Alternate Names:
NCH 51; S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate
Application:
PTACH is a potent HDAC inhibitor
CAS Number:
848354-66-5
Purity:
≥98%
Molecular Weight:
390.56
Molecular Formula:
C20H26N2O2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
PTACH is a cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor, with an IC50 of 48 nM. PTACH is predicted to exhibit a similar HDAC binding mode as that of SAHA, interacting with the active-site zinc targeting group.
PTACH (CAS 848354-66-5) References
Suzuki, T., et al., Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. J. Med. Chem. 48, 1019-1032, (2005)Inhibitor of:
HDAC.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PTACH, 2 mg | sc-253326 | 2 mg | $216.00 |