Molecular structure of PSB 10 hydrochloride, CAS Number: 591771-91-4
PSB 10 hydrochloride (CAS 591771-91-4)
Alternate Names:
8-Ethyl-1,4,7,8-tetrahydro-4-methyl-2-(2,3,5-trichlorophenyl)-5H-imidazo[2,1-i]purin-5-one monohydrochloride
Application:
PSB 10 hydrochloride is a potent and highly selective antagonist for the Adenosine A3-R
CAS Number:
591771-91-4
Molecular Weight:
435.14
Molecular Formula:
C16H14Cl3N5O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
PSB 10 is a potent and highly selective antagonist for the human Adenosine A3-R, with low affinity for the rat Adenosine A3-R (Ki values are 0.44 and > 17000 nM, respectively). PSB 10 Displays > 3800-fold selectivity over human Adenosine A1-R, Adenosine A2A-R and Adenosine A2B-R (Ki values are 4.1, 3.3 and 30 μM, respectively) and > 1800-fold selectivity over rat Adenosine A1-R and Adenosine A2A-R. This compound acts as an inverse agonist in the [35S]GTPγS binding assay in hA3-CHO cells (IC50 = 4 nM).
PSB 10 hydrochloride (CAS 591771-91-4) References
1. Muller, C.E. 2003. Curr. Top. Med. Chem. 3: 445-462.2. Ozola, V., et al. 2003. Bioorg. Med. Chem. 11: 347-356.
3. Abo-Salem, O.M., et al. 2004. J. Pharmacol. Exp. Ther. 308: 358-366.
Inhibitor of:
Adenosine A3-R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSB 10 hydrochloride, 10 mg | sc-203669 | 10 mg | $199.00 | |||
| US: Only available in the US | ||||||
PSB 10 hydrochloride, 50 mg | sc-203669A | 50 mg | $849.00 | |||
| US: Only available in the US | ||||||