PSA (h2): 293T Lysate is derived from the human embryonic kidney 293T cell line, which has been transfected to express the human Prostate-Specific Antigen (PSA). PSA is a serine protease belonging to the kallikrein family, primarily involved in the liquefaction of semen in the male reproductive system. The 293T cell line, characterized by its high transfection efficiency and robust protein expression, provides a reliable source for PSA production. In research, PSA (h2): 293T Lysate is used to explore the biochemical pathways involving PSA and its enzymatic activity. PSA functions by cleaving semenogelins in seminal fluid, a process critical for semen liquefaction. Research applications include studying PSA's role in proteolytic cascades, understanding its substrate specificity, and investigating the regulatory mechanisms of its expression and activity. Additionally, PSA (h2): 293T Lysate is utilized in immunoassays, such as Western blotting and ELISA, to detect and quantify PSA and its isoforms. This lysate is also instrumental in analyzing PSA's interaction with other proteins and its potential involvement in various physiological processes. The detailed examination of PSA using this lysate enhances our understanding of its biological functions and regulatory mechanisms in cellular contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSA/KLK3/Kallikrein 3/Prostate Specific Antigen (h2): 293T Lysate | sc-170195 | 100 µg/200 µl | $236.00 |