Date published: 2026-4-30

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Prothipendyl Hydrochloride (CAS 1225-65-6)

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Alternate Names:
Dominal Hydrochloride; Prothipendyl Monohydrochloride; Tolnate
CAS Number:
1225-65-6
Molecular Weight:
321.87
Molecular Formula:
C16H20ClN3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Prothipendyl hydrochloride (PT-HCl) is a synthetic compound derived from the naturally occurring alkaloid prothipendyl, which can be found in several plants belonging to the Apocynaceae family. This derivative, prothipendyl hydrochloride, is known to function as a reversible inhibitor of monoamine oxidase (MAO), an enzyme responsible for the breakdown of neurotransmitters like serotonin and dopamine. By exerting its inhibitory effect on MAO activity, prothipendyl hydrochloride promotes an elevation in the levels of these neurotransmitters within the brain. Consequently, this increase can yield a range of effects, including heightened alertness, enhanced mood, and elevated energy levels. It is believed that prothipendyl hydrochloride achieves these outcomes by modulating the neurochemical balance and dynamics, thereby influencing various aspects of mental and emotional states.


Prothipendyl Hydrochloride (CAS 1225-65-6) References

  1. Application of ammonium peroxidisulfate and metavanadate for spectrophotometric determination of prothipendyl hydrochloride.  |  Misiuk, W. and Kleszczewska, E. 2001. Acta Pol Pharm. 58: 87-92. PMID: 11501795
  2. Sensitive and Rapid Voltammetric Determination of Phenothiazine and Azaphenothiazine Derivatives in Pharmaceuticals Using a Boron-doped Diamond Electrode.  |  Mielech-Łukasiewicz, K. and Staśkowska, E. 2015. Anal Sci. 31: 961-9. PMID: 26460359
  3. Analysis of cardiopulmonary findings in COVID-19 fatalities: High incidence of pulmonary artery thrombi and acute suppurative bronchopneumonia.  |  Grosse, C., et al. 2020. Cardiovasc Pathol. 49: 107263. PMID: 32784110

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prothipendyl Hydrochloride, 10 mg

sc-477102
10 mg
$380.00