Date published: 2026-4-25

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Prothiofos (CAS 34643-46-4)

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CAS Number:
34643-46-4
Molecular Weight:
345.25
Molecular Formula:
C11H15Cl2O2PS2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Prothiofos, a widely utilized organophosphate insecticide, has been a prominent choice for pest control in agricultural, industrial, and residential settings for many decades. Its effectiveness and cost-efficiency have made it one of the most used insecticides globally. Prothiofos has also been extensively studied in scientific research, encompassing investigations into its toxic effects on humans and animals, its environmental fate, and its potential as a pesticide. Furthermore, studies have been conducted on its metabolic fate and potential for biodegradation.


Prothiofos (CAS 34643-46-4) References

  1. Prothiofos metabolites in human poisoning.  |  Sakata, M., et al. 1999. J Toxicol Clin Toxicol. 37: 327-32. PMID: 10384797
  2. Migration of organophosphorus insecticides cyanophos and prothiofos residues from impregnated paper bags to Japanese apple-pears (Pyrus pyrifolia nakai cv. Nijisseiki).  |  Katami, T., et al. 2000. J Agric Food Chem. 48: 2499-501. PMID: 10888575
  3. Rainfall-induced sediment and pesticide input from orchards into the Lourens River, Western Cape, South Africa: importance of a single event.  |  Schulz, R. 2001. Water Res. 35: 1869-76. PMID: 11337831
  4. Contamination of rural surface and ground water by endosulfan in farming areas of the Western Cape, South Africa.  |  Dalvie, MA., et al. 2003. Environ Health. 2: 1. PMID: 12689341
  5. Mutations of acetylcholinesterase1 contribute to prothiofos-resistance in Plutella xylostella (L.).  |  Lee, DW., et al. 2007. Biochem Biophys Res Commun. 353: 591-7. PMID: 17196934
  6. Temporal variability in particle-associated pesticide exposure in a temporarily open estuary, Western Cape, South Africa.  |  Bollmohr, S., et al. 2007. Chemosphere. 68: 479-88. PMID: 17287007
  7. Cultivable bacteria associated with larval gut of prothiofos-resistant, prothiofos-susceptible and field-caught populations of diamondback moth, Plutella xylostella and their potential for, antagonism towards entomopathogenic fungi and host insect nutrition.  |  Indiragandhi, P., et al. 2007. J Appl Microbiol. 103: 2664-75. PMID: 17973916
  8. Poisoning with the S-Alkyl organophosphorus insecticides profenofos and prothiofos.  |  Eddleston, M., et al. 2009. QJM. 102: 785-92. PMID: 19737786
  9. Fate of 14C-ethyl prothiofos insecticide in canola seeds and oils.  |  Abdel-Gawad, H. and Hegazi, B. 2010. J Environ Sci Health B. 45: 116-22. PMID: 20390940
  10. Combination of vortex assisted binary solvent microextraction and QuEChERS for the determination of prothiofos, oxadiargyl, and gamma-cyhalothrin in water and pineapple samples by gas chromatography mass spectrometry.  |  Budak, TB., et al. 2020. Environ Monit Assess. 192: 273. PMID: 32266493
  11. Development of a strategic approach for comprehensive detection of organophosphate pesticide metabolites in urine: Extrapolation of cadusafos and prothiofos metabolomics data of mice to humans.  |  Nomasa, K., et al. 2021. J Occup Health. 63: e12218. PMID: 33779022
  12. Melt intercalation technique for synthesis of hetero-metallic@chitin bio-composite as recyclable catalyst for prothiofos hydrolysis.  |  Emam, HE., et al. 2021. Carbohydr Polym. 266: 118163. PMID: 34044959
  13. Assessment of organophosphate pesticide residues in environmental media of Araromi farm settlement, Osun State, Nigeria.  |  Awe, YT., et al. 2022. Environ Anal Health Toxicol. 37: e2022035-0. PMID: 36916048

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prothiofos, 100 mg

sc-250798
100 mg
$84.00