


QUICK LINKS
Protein C Antibody (HLW-C) is a mouse monoclonal IgG2b antibody that detects Protein C in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Protein C is a crucial vitamin K-dependent plasma protein synthesized in the liver, consisting of two polypeptide chains, and plays a vital role in the regulation of blood coagulation. Upon activation by thrombin bound to an endothelial surface receptor, Protein C enzymatically cleaves activated forms of coagulation Factors V and VIII, thereby inhibiting excessive blood clotting and maintaining hemostatic balance. The normal concentration of Protein C in human plasma ranges from approximately 1-3 ng/ml, while the proenzyme concentration is around 3 µg/ml. Deficiencies in Protein C can lead to inherited thrombophilia, a genetic disorder that significantly increases the risk of venous thrombosis and complications such as habitual abortion. Understanding the structure of Protein C is essential, as Protein C shares similarities with the prothrombin group of coagulation factors, which underscores its importance in the coagulation cascade and highlights the potential implications of its dysfunction in thrombotic disorders. Anti-Protein C antibody (HLW-C) is an invaluable tool for researchers studying coagulation pathways and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Protein C Antibody (HLW-C) | sc-69662 | 100 µg/ml | $322.00 |