Protein C Antibody (GMA-067): sc-65958
- Protein C Antibody (GMA-067) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against Protein C of human origin, with epitope mapping to Protein C heavy chain
- recommended for detection of Protein C of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Protein C Antibody (GMA-067). This work is in progress.
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Protein C Antibody (GMA-067) is a mouse monoclonal IgG1 antibody that detects Protein C in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Protein C is a crucial vitamin K-dependent plasma protein synthesized in the liver, consisting of two polypeptide chains. Anti-Protein C antibody (GMA-067) plays a vital role in studying blood coagulation regulation, where Protein C acts as an anticoagulant; upon activation by thrombin bound to an endothelial surface receptor, Protein C enzymatically cleaves activated forms of coagulation factors V and VIII, thereby inhibiting excessive blood clotting. The proper functioning of Protein C is essential for maintaining hemostatic balance, as deficiencies can lead to inherited thrombophilia, a genetic disorder that significantly increases the risk of venous thrombosis and complications such as habitual abortion. Normal levels of Protein C in human plasma range from approximately 1-3 ng/ml, while the proenzyme concentration is around 3 µg/ml. Protein C monoclonal antibody (GMA-067) serves as an invaluable tool for researchers studying coagulation pathways and related disorders, providing insights into the mechanisms of thrombosis and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Protein C Antibody (GMA-067) | sc-65958 | 100 µg/ml | $322.00 |