Molecular structure of Prostaglandin F2α serinol amide
Prostaglandin F2α serinol amide
Application:
Prostaglandin F2α serinol amide is a stable analog of PGF2α 2-glyceryl ester
Molecular Weight:
427.57
Molecular Formula:
C23H41NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Exhibits cannabinoid agonist activity at the CB1 receptor,1 is an important endogenous monoglyceride species,2 and is therefore considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by COX-2 and prostaglandin D, E, F, and I synthases to form prostaglandin 2-glyceryl (PG 2-glyceryl) esters.3 PGF2α-SA is a stable analog of PGF2α 2-glyceryl ester.
Prostaglandin F,[object Object], serinol amide References
- Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. | Kozak, KR., et al. 2002. J Biol Chem. 277: 44877-85. PMID: 12244105
- Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. | Fowler, CJ. and Tiger, G. 2005. Biochem Pharmacol. 69: 1241-5. PMID: 15794945
- Harnessing probiotics capability to combat Salmonella Heidelberg and improve intestinal health in broilers. | Hoepers, PG., et al. 2024. Poult Sci. 103: 103739. PMID: 38678973
- Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells. | Sugiura, T., et al. 1997. J Biochem. 122: 890-5. PMID: 9399597
- 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through CA2+-dependent and -independent mechanisms. | Kondo, S., et al. 1998. FEBS Lett. 429: 152-6. PMID: 9650580
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin F2α serinol amide, 1 mg | sc-224227 | 1 mg | $68.00 | |||
Prostaglandin F2α serinol amide, 5 mg | sc-224227A | 5 mg | $305.00 |