Molecular structure of Prostaglandin F2α Ethanolamide, CAS Number: 353787-70-9
Prostaglandin F2α Ethanolamide (CAS 353787-70-9)
Alternate Names:
Dinoprost Ethanolamide; PGF2α-EA
Application:
Prostaglandin F2α Ethanolamide is a PGF2α analog formed via Anandamide which acts as a substrate for cyclooxygenase
CAS Number:
353787-70-9
Molecular Weight:
397.5
Molecular Formula:
C22H39NO5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Prostaglandin F2α ethanolamide (PGF2α-EA) is a PGF2α (sc-201227) analog formed via Anandamide (Arachinodoyl Ethanolamine; AEA; sc-200790), an endogenous cannabinoid, which acts as a substrate for cyclooxygenase. The conversion of AEA to prostaglandins has been demonstrated with many different eicosanoids, some of which display unique biological activity. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which has been used as a model system for testing potential intraocular hypotensive agents.
Prostaglandin F2α Ethanolamide (CAS 353787-70-9) References
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- Recent progress in prostaglandin F2α ethanolamide (prostamide F2α) research and therapeutics. | Woodward, DF., et al. 2013. Pharmacol Rev. 65: 1135-47. PMID: 23893067
- Identification of prostamides, fatty acyl ethanolamines, and their biosynthetic precursors in rabbit cornea. | Urquhart, P., et al. 2015. J Lipid Res. 56: 1419-33. PMID: 26031663
- Potential antitumor agents. 24. Dicationic analogues of the 4'-(9-acridinylamino)alkanesulfonanilides. | Atwell, GJ., et al. 1977. J Med Chem. 20: 1128-34. PMID: 926112
- The Pharmacology of Prostaglandin F2α Ethanolamide and Bimatoprost Reveals a Unique Feedback Mechanism on Endocannabinoid Actions[M]// | Woodward D F, Wang J W., 2015. The Endocannabinoidome. Academic Press.: 85-99.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin F2α Ethanolamide, 1 mg | sc-205463 | 1 mg | $70.00 | |||
Prostaglandin F2α Ethanolamide, 5 mg | sc-205463A | 5 mg | $321.00 |