Date published: 2026-8-2

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Prostaglandin F 1,11-lactone (CAS 62410-84-8)

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Alternate Names:
9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1,11-lactone
Application:
Prostaglandin F 1,11-lactone is a lipid-soluble ester of PGF
CAS Number:
62410-84-8
Molecular Weight:
336.5
Molecular Formula:
C20H32O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone by plasma esterases readily produces free PGF2α in rats and monkeys, but not in humans.1 PGF2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity compared to PGF2α.1


Prostaglandin F,[object Object], 1,11-lactone (CAS 62410-84-8) References

  1. Azelaic acid and guanosine in tears improve discrimination of proliferative from non-proliferative diabetic retinopathy in type-2 diabetes patients: A tear metabolomics study.  |  Wen, X., et al. 2023. Heliyon. 9: e16109. PMID: 37305454
  2. Untargeted metabolomics yields insight into extramammary Paget's disease mechanisms.  |  Jiang, L., et al. 2024. Front Oncol. 14: 1319819. PMID: 38347841
  3. Advanced Mass Spectrometry-Based Biomarker Identification for Metabolomics of Diabetes Mellitus and Its Complications.  |  Zhang, F., et al. 2024. Molecules. 29: PMID: 38893405
  4. Synthesis and biological activity of prostaglandin lactones.  |  Bundy, GL., et al. 1983. J Med Chem. 26: 1089-99. PMID: 6876076

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prostaglandin F 1,11-lactone, 1 mg

sc-205459
1 mg
$84.00

Prostaglandin F 1,11-lactone, 5 mg

sc-205459A
5 mg
$379.00