Molecular structure of Prostaglandin F1α-d9
Prostaglandin F1α-d9
Application:
Prostaglandin F1α-d9 is an internal standard for the quantification of PGF1α by GC- or LC-mass spectrometry
Molecular Weight:
365.6
Molecular Formula:
C20H27D9O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Contains nine deuterium atoms at the 17, 17′, 18, 18′, 19, 19′, 20, 20, and 20 positions and is intended for use as an internal standard for the quantification of PGF1α by GC- or LC-mass spectrometry. PGF1α is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M.1 PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α.2 but it is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.3
Prostaglandin F1α-d9 References
1 Moore, A., Waring, C.P. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J Exp Biol 199 2307-2316 (1996). 2 Balapure, A.K., Rexroad, C.E., Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochem Pharmacol 38 2375-2381 (1989). 3 Karim, S.M.M., Adaikan, P.G., Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin F1α-d9, 25 µg | sc-224223 | 25 µg | $64.00 | |||
Prostaglandin F1α-d9, 50 µg | sc-224223A | 50 µg | $121.00 |