Molecular structure of Prostaglandin E2-PEG11-biotinamide
Prostaglandin E2-PEG11-biotinamide
Alternate Names:
Prostaglandin E2-polyethyleneglycol-11-biotinamide
Application:
Prostaglandin E2-PEG11-biotinamide is a derivative of PGE2 designed to allow PGE2 to be detected or immobilized using the biotin ligand
Molecular Weight:
1105.4
Molecular Formula:
C54H96N4O17S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Prostaglandin E2-PEG11-biotinamide is a functionalized derivative of PGE2 (sc-201225) - the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid (sc-200770) by COX and PGES, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects. This compound was designed to allow PGE2 to be detected or immobilized using the biotin ligand. The polyethylene glycol linker serves as a hydrophillc spacer that separates the biotin moiety from the active PGE2 part of the molecule allowing for the elucidation of PGE2 actions or interactions in aqueous solutions.
Prostaglandin E2-PEG11-biotinamide References
- Prostaglandin E2, a seminal constituent, facilitates the replication of acquired immune deficiency syndrome virus in vitro. | Kuno, S., et al. 1986. Proc Natl Acad Sci U S A. 83: 3487-90. PMID: 3010301
- Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms. | Miller, TA. 1983. Am J Physiol. 245: G601-23. PMID: 6195926
- Effect of prostaglaidin endoperoxides and metabolites on bone resorption in vitro. | Raisz, LG., et al. 1977. Nature. 267: 532-4. PMID: 876371
- The vasodilator actions of isoprenaline, histamine, prostaglandin E2, glucagon and secretin on the hepatic arterial vascular bed of the dog. | Richardson, PD. and Withrington, PG. 1976. Br J Pharmacol. 57: 581-8. PMID: 963344
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin E2-PEG11-biotinamide, 50 µg | sc-224222 | 50 µg | $80.00 | |||
Prostaglandin E2-PEG11-biotinamide, 100 µg | sc-224222A | 100 µg | $152.00 |